Vestibular migraine and its management in Indian clinical setting: a narrative review

Authors

  • Ilambarathi M. GNET Clinic, Velan Building, Main Nanganallur, Chennai, Tamil Nadu, India
  • Avinash Bijlani Madhaw Medical Centre, Old Rajinder Nagar, Delhi, India
  • Dhrubo Roy AMRI Hospital, Mukundpur, Kolkata, West Bengal, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20233517

Keywords:

Vestibular migraine, Acute vertigo, Prochlorperazine, Migraine-associated vertigo

Abstract

Vestibular migraine (VM) is a disorder connecting two clinical conditions, migraine and vertigo. A high prevalence of VM (~30%) is reported among Indians suffering from dizziness. Yet, there is no gold standard for diagnosis and treatment. Trials specifically for patients with VM are scarce. This review provides an overview on VM and its management in the Indian clinical setting. An evidence-based discussion and review of literature on VM was performed by expert panelists, and opinions were gathered. Experts opined that in vertigo clinics, around 50% of patients are diagnosed with VM, with a higher predominance in females aged 30-50 years, while in children, the age of manifestation is 12-14 years. The most common presenting symptoms of VM among adults are spontaneous vertigo, followed by positional vertigo with headache, nausea, vomiting, photophobia and phonophobia, while intolerance to loud sounds and sudden falls are common symptoms in children with VM. Common comorbidities associated with VM are benign paroxysmal positional vertigo (BPPV) and Meniere’s disease (MD). Experts opined that there are currently no approved standardized treatment protocols for VM. The steps in the management of VM include diet and lifestyle modification, along with medicines for symptomatic relief (abortive) and prophylaxis and vestibular rehabilitation. Globally, prochlorperazine, a vestibular suppressant, is widely used for the management of vertigo and its associated symptoms. According to experts, prochlorperazine 5 mg twice or thrice daily for 5-7 days can play a significant role as an abortive treatment in the management of various patient profiles of VM.

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References

Nowaczewska M. Vestibular migraine-An underdiagnosed cause of vertigo. Diagnosis and treatment. Neurol Neurochir Pol. 2020;54(2):106-15.

Dieterich M, Obermann M, Celebisoy N. Vestibular migraine: the most frequent entity of episodic vertigo. J Neurol. 2016;263(1):S82-9.

Lempert T, Neuhauser H. Epidemiology of vertigo, migraine and vestibular migraine. J Neurol. 2009;256(3):333-8.

Sohn JH. Recent Advances in the Understanding of Vestibular Migraine. Behav Neurol. 2016;2016:180.

The international classification of headache disorders. Available at: https://ichd-3.org/. Accessed on 13 March 2023.

Headache Classification Committee of the International Headache Society. The International Classification of Headache Disorders. Cephalalgia. 2013;33(9):629-808.

Mallampalli MP, Rizk HG, Kheradmand A, Beh SC, Abouzari M, Bassett AM, et al. Care Gaps and Recommendations in Vestibular Migraine: An Expert Panel Summit. Front Neurol. 2022;12:812.

Swain SK, Debta P, Lenka S, Samal S, Dani A, Mahapatra S, et al. Vestibular migraine-A Challenging Clinical Entity. Indian J Forensic Med Toxicol. 2020;14;8835-41.

Swain SK, Behera IC, Sahoo L. Vestibular migraine: Our experiences at a tertiary care teaching hospital of Eastern India. Med J DY Patil Vidyapeeth. 2020;13:636-41.

Brodsky JR, Cusick BA, Zhou G. Evaluation and management of vestibular migraine in children: Experience from a pediatric vestibular clinic. Eur J Paediatr Neurol. 2016;20(1):85-92.

Langhagen T, Lehrer N, Borggraefe I, Heinen F, Jahn K. Vestibular migraine in children and adolescents: clinical findings and laboratory tests. Front Neurol. 2015;5:292.

Barbosa F, Villa TR. Vestibular migraine: diagnosis challenges and need for targeted treatment. Arq Neuropsiquiatr. 2016;74(5):416-22.

Lempert T, von Brevern M. Vestibular Migraine. Neurol Clin. 2019;37(4):695-706.

Eggers SD, Neff BA, Shepard NT, Staab JP. Comorbidities in vestibular migraine. J Vestib Res. 2014;2:387-95.

Shin CH, Kim Y, Yoo MH, Kim TS, Park JW, Kang BC, et al. Management of Ménière's disease: How does the coexistence of vestibular migraine affect outcomes? Otol Neurotol. 2019;40:666-73.

Waterston J, Chen L, Mahony K, Gencarelli J, Stuart G. Persistent postural-perceptual dizziness: Precipitating conditions, co-morbidities and treatment with cognitive behavioral therapy. Front Neurol. 2021;12:795.

Shankar Kikkeri N, Nagalli S. Migraine with Aura. Available at: https://www.ncbi.nlm.nih. gov/NBK554611/. Accessed on 13 March 2023.

Eigenbrodt AK, Ashina H, Khan S, Diener HC, Mitsikostas DD, Sinclair AJ, et al. Diagnosis and management of migraine in ten steps. Nat Rev Neurol. 2021;17:501-14.

Hilton DB, Shermetaro C. Migraine-Associated Vertigo. Available at: https://www.ncbi.nlm.nih. gov/NBK507859/. Accessed on 13 March 2023.

Vestibular migraine. Available at: https://www. hopkinsmedicine.org/health/conditions-and-diseases/vestibular-migraine#:~:text=Migraine%20 headaches%20are%20a%20common,%2C%20imbalance%2C%20nausea%20and%20vomiting. Accessed on 13 March 2023.

Huang TC, Wang SJ, Kheradmand A. Vestibular migraine: An update on current understanding and future directions. Cephalalgia. 2020;40:107-21.

Perez-Carpena P, Lopez-Escamez JA. Do we need to reconsider the classification of vestibular migraine? Expert Rev Neurother. 2021;21(5):503-16.

Vivek S, Prem G, Dorasala S, Faiza B, Joy M, Nair AS. Videonystagmography (VNG) findings in patients with vestibular migraine: A hospital-based study. Indian J Otolaryngol Head Neck Surg. 2022;74(3):S4290-7.

Bijlani A, John S, Srinivas D, Nayar R. Vestibular migraine-a diagnostic dilemma (a case report with review of literature. Onl J Otolaryngol Rhinol. 2019;5:19-23.

Strupp M, Lopez-Escamez JA, Kim JS, Straumann D, Jen JC, Carey J, et al. Vestibular paroxysmia: Diagnostic criteria. J Vestib Res. 2016;26:409-15.

Shen Y, Qi X. Update on diagnosis and differential diagnosis of vestibular migraine. Neurol Sci. 2022;43:1659-66.

Swain SK, Shajahan N, Acharya S. A scoping review of vestibular paroxysmia: An acute disabling clinical entity. J Acute Dis. 2020;9:248-52.

Dikmen PY. Diagnosis and treatment in vestibular migraine. Turk J Neurol. 2020;26:260-8.

Smyth D, Britton Z, Murdin L, Arshad Q, Kaski D. Vestibular migraine treatment: a comprehensive practical review. Brain. 2022;145(11):3741-54.

Tsang B K-T. Diagnosis and management of vestibular migraine. J Clin Outcomes Manage. 2015;22(10):32-8.

Kameshwaran M, Sarda K. Therapeutic interventions in vertigo management. Int J Otorhinolaryngol Head Neck Surg. 2017;3:777-85.

Obermann M, Strupp M. Current treatment options in vestibular migraine. Front Neurol. 2014;5:257.

Kumar A, Kadian R. Migraine prophylaxis. Available at: https://www.ncbi.nlm.nih.gov/books/NBK507873/ Accessed on 13 March 2023

Bisdorff AR. Management of vestibular migraine. Ther Adv Neurol Disord. 2011;4:183-91.

Shen Y, Qi X, Wan T. The treatment of vestibular migraine: A narrative review. Ann Indian Acad Neurol. 2020;23:602-7.

Migraine without aura. Available at: https://america nmigrainefoundation.org/resource-library/migraine-without-aura/. Accessed on 13 March 2023.

Cha YH. Migraine-associated vertigo: diagnosis and treatment. Semin Neurol. 2010;30:167-74.

Vestibular migraine. Available at: https://migraine trust.org/understand-migraine/types-of-migraine/vesibular/. Accessed on 13 March 2023.

Kacperski J, Kabbouche MA, O'Brien HL, Weberding JL. The optimal management of headaches in children and adolescents. Ther Adv Neurol Disord. 2016;9:53-68.

Viola P, Marcianò G, Casarella A, Pisani D, Astorina A, Scarpa A,. The Pharmacological Treatment of Pediatric Vertigo. Children. 2022;9:584.

Haldipur D, Krishnamurthy NAB. The real-world safety and effectiveness of prochlorperazine in Indian patients with dizziness. J Assoc Physicians India. 2020;68(2):61-6.

Comprehensive management of acute dizziness and role of prochlorperazine. Indian Acad Neurol. 2019;20:152-7.

Prabhat D, Kiran G. Clinicoepidemiological profile and practices to manage dizziness in primary care setting: results from an Indian registry. Int J Otorhinolaryngol Head Neck Surg. 2021;7:320-30.

Golikhatir I, Cheraghmakani H, Bozorgi F, Jahanian F, Sazgar M, et al. The efficacy and safety of prochlorperazine in patients with acute migraine: A systematic review and meta-analysis. Headache. 2019;59:682-700.

Munice HL, Sirmans SM, James E. Dizziness: Approach to evaluation and management. Am Fam Physician. 2017;95:154-62.

Prochlorperazine. Available at: https://www.nhs. uk/medicines/prochlorperazine/. Accessed on 13 March 2023.

Gnerre P, Casati C, Frualdo M, Cavalleri M, Guizzetti S. Management of vertigo: From evidence to clinical practice. Italian J Med. 2015;9:180-92.

Kuo CH, Pang L, Chang R. Vertigo - part 2 - management in general practice. Aust Fam Physician. 2008;37:409-13.

Vertigo. Available at: https://www.entuk.org/ patients/conditions/18/vertigo/. Accessed on 13 March 2023.

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Published

2023-11-06

How to Cite

M., I., Bijlani, A., & Roy, D. (2023). Vestibular migraine and its management in Indian clinical setting: a narrative review. International Journal of Otorhinolaryngology and Head and Neck Surgery, 9(12), 1003–1010. https://doi.org/10.18203/issn.2454-5929.ijohns20233517

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Section

Review Articles