Efficacy of platelet rich fibrin in myringoplasty


  • Disha Sharma Department of Otolaryngology- Head and Neck Surgery, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
  • Shobha Mohindroo Department of Pathology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
  • Ramesh K. Azad Department of Otolaryngology- Head and Neck Surgery, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India




Graft, Myringoplasty, PRF, 500 hz, 1000 hz, 2000 hz


Background: Myringoplasty involves repair of tympanic membrane perforation with an autologous graft.The aim was to compare between myringoplasty with PRF and myringoplasty without fibrin.

Methods: This study was conducted from July 2016 to June 2017,100 patients were taken. In 50 patients platelet rich fibrin was placed over graft and external auditory canal during myringoplasty and 50 without PRF.  

Results: It was seen in the study that PRF improves overall success rate of myringoplasty study and there was significant improvement in ABG at 500 hz, 1000 hz, 2000 hz frequencies.

Conclusions: The higher success rate of myringoplasty with PRF was seen as compared to myringoplasty without fibrin. There were no noticeable side effects.


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Original Research Articles