Metastatic renal cell carcinoma in the head and neck region
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20182721Keywords:
Renal cell carcinoma, Metastasis, Head and neckAbstract
We describe 3 rare cases of metastatic renal cell carcinoma in the head and neck region. Our first case was a 72 years old male presented with profuse bleeding from the left ear. On examination, proliferative, pink, friable mass was present in the left external auditory canal. On eliciting the detailed history, it was found that patient had renal cell carcinoma in the left kidney four years back and underwent left radical nephrectomy. Patient underwent left lateral temporal bone resection with cul-de-sac closure. Histopathological examination of the specimen showed metastatic renal cell carcinoma. Our second case was a 64 years old male presented with complaints of growth in the oral cavity of 1 month duration. On examination, 5×3 cms proliferative growth was present in the hard palate. Biopsy from the growth in the hard palate showed metastatic renal cell carcinoma. Patient gave history of renal cell carcinoma in the past for which he did not receive treatment. Our third case was a 45 years old male who presented to us with a diffuse swelling in the left temporal region of 2 months duration. On examination, 3×2 cms swelling was present in the left temporal region. Patient had history of renal cell carcinoma of left kidney and underwent left nephrectomy one year prior to the presentation of the left temporal swelling. Ultrasonography guided biopsy of the left temporal region showed metastatic renal cell carcinoma.
References
Motzer RJ, Bander NH, Nanus DM. Renal cell carcinoma. New England J Med. 2012;335(12):865-873.
Ingelaere PPC, Simpson RHW, Garth RJN. Metastatic renal cell carcinoma presenting as an aural polyp. J Laryngol Otol. 1997;3:1066-8.
Seijas BP, Franco FL, Sastre RM, Garcia AA, Lopez JL. Metastatic renal cell carcinoma presenting as a parotid tumor. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:554-7.
Flanigan RC, Campbell SC, Clark JI, Picken MM. Metastatic renal cell carcinoma. Current treatment options in oncology. 2003;4:385-90.
Atzopodien J, Kirchner H, Illiger HJ, Metzner B, Ukena D, Schott H, et al. IL-2 in combination with IFN-alpha and 5 FU versus tamoxifen in metastatic renal cell carcinoma: long term results of a controlled randomised trial. Br J Cancer. 2001;85(8):1130-6.
Pritchyk KM, Schiff BA, Newkirk KA, Krowiak E, Deeb ZE. Metastatic Renal cell carcinoma to the head and neck. Laryngoscope. 2002;112:1598-602.
Shenoy A, Jyothy S, Rao K, Hazarika P. Carcinoma of External Auditory Canal. Indian J Otolaryngol Head Neck Surg. 2011;53(3):229-31.
Devaney KO, Boschman CR, Willard SC, Ferlito A, Rinaldo A. Tumours of the external ear and temporal bone. Lancet Oncol. 2005;6:411-20.
Vasileiadis I, Kapetanakis S, Vasileiadis D, Petoutis A, Karatzas T. External Auditory Canal Mass as the first manifestation of a Bronchogenic Carcinoma: Report of a rare case. Ann Otol Rhinol Laryngol. 2013;122(6):378-81.
Michaelson PG, Lowry TR. Metastatic renal cell carcinoma presenting in the external auditory canal. Otolaryngol Head Neck Surg. 2005;133:979-80.
Hoffmann NE, Gillett MD, Cheville JC, Lohse CM, Leibovich BC, Blute ML. Differences in organ system of distant metastasis by renal cell carcinoma subtypes. J Urol. 2008;179:474-7.
Will TA, Agarwal N, Petruzzelli GJ. Oral cavity metastasis of renal cell carcinoma: A case report. J Med Case Reports. 2008;2:313.
Azam F, Abubakerr M, Gollins S. Tongue metastasis as an initial presentation of renal cell carcinoma: a case report and literature review. J Med Case Reports. 2008;2:249.
