DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20181891

Squamous cell carcinoma of tympano-mastoid region: a series of six cases

Surender Kumar, Uma Garg, Naveen Sharma, Neha Salaria, Deepak Verma

Abstract


The malignancies of tympanomastoid region are very rare entity. These tumours are more common in elderly persons in 6th and 7th decade. Males are more commonly affected than females. Chronically discharging ears are considered as risk factor which may be due to metaplasia in the middle ear mucosa following prolonged chronic infection. The most common symptoms are long standing blood tinged ear discharge, severe nocturnal pain, rapidly growing polypoidal or granulomatous mass in EAC or middle ear, peripheral facial palsy and painless ulceration over pinna or EAC. CT scan for bony erosion and MRI for soft tissue involvement and neural invasion are investigations of choice. Tissue biopsy is must for histopathological examination and confirmation of diagnosis. Surgery and chemo-radiotherapy are the mainstay of treatment. Surgery includes wide local excision, lateral temporal bone resection, subtotal temporal bone resection and total temporal bone resection.

 


Keywords


Squamous cell carcinoma, Tympanomastoid malignancy, Temporal bone resection, Chemo-radiotherapy

Full Text:

PDF

References


National Cancer Institute. “Cancer facts. Head and neck cancer: questions and answers.” Available at: http://www.cancer.gov/cancertopics/factsheet/Sites-types/head-and-neck/. Accessed on 3 February 2018.

Lionello M, Stritoni P, Facciolo MC, Staffieri A, Martini A,Mazzoni A, et al. Temporal bone carcinoma. Current diag-nostic, therapeutic, and prognostic concepts. J Surg Oncol. 2014;110:383-92.

Gidley PW, Roberts DB, Sturgis EM. Squamous cell carcinoma of the temporal bone. Lary-ngoscope 2010;120:1144-51.

Shu MT, Lee JC, Yang CC, Wu KC. Squamous cell carcinoma of the middle ear. Ear Nose Throat J. 2012;91:14.

Cureoglu S, Tulunay O, Ferlito A, Schachern PA, Paparella MM, Rinaldo A. Otologic manifestations of metastatic tumors to thetemporal bone. Acta Otolaryngol. 2004;124:1117-23.

Elsürer C, Senkal HA, Zayyan E, Yilmaz T, Kaya S. Bilateral external auditory canal squamous cell carcinoma: a case report. Eur Arch Otor-hinolaryngol. 2007;264:941-5.

Monem SA, Moffat DA, Frampton MC. Carcinoma of the ear: a case report of a possible association with chlorinated disinfec-tants. J Laryngol Otol. 1999;113:1004-7.

Gaio E, Marioni G, Blandamura S, Staffieri A. Inverted papiloma involving the temporal bone and its association with squamous cell carcinoma: critical analysis of the literature. Expert Rev Anticancer Ther. 2005;5:391-7.

Marioni G, Altavilla G, Busatto G, Blandamura S, De Filippis C, Staffieri A. Detection of human papillomavirus in temporal bone inverted papilloma by polymerase chain reaction. Acta Otolaryngol. 2003;123:367-71.

Niparko JK, Swanson NA, Baker SR, Telian SA, Sullivan MJ, Kemink JL. Local control of auricular, periauricular, and external canal cutaneous malignancies with Mohs surgery. Laryngoscope. 1990;100:1047-51.

Gal TJ, Futran ND, Bartels LJ, Klotch DW. Auricular carcinoma with temporal bone invasion: outcome analysis. Otolaryngol Head Neck Surg. 1999;121:62-5.

Gaudet JE, Walvekar RR, Arriaga MA, Dileo MD, Nuss DW, Pou AM, et al. Applicability of the Pittsburgh staging system for advanced cutaneous malignancy of the temporal bone. Skull Base. 2010;20:409-14.