Rosai Dorfman disease: a case report
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20180730Keywords:
Rosai Dorfman disease, Sinus histiocytosis, Massive lymphadenopathy, EmperipolesisAbstract
Rosai Dorfman disease (RDD) is a rare granulomatous disease that typically presents with massive lymphadenopathy. To our knowledge, there have only been 650 cases reported worldwide. It is more common among adults and has characteristic clinical, radiological and histopathological findings. Here, we present a case of RDD in a 51 year-old man with massive submental lymphadenopathy which was not responding to antibiotics. Computerized Tomographic Scan showed ill-defined non-enhancing soft tissue density while fine needle aspiration for cytology displayed emperipolesis which is seen in patients with RDD. The swelling followed a benign course and reduced in size progressively without further intervention.
Metrics
References
Histiocyte Society. Rosai Dorfman Disease, 2011. Available at: https://histiocytesociety.org/ document.doc?id=54. Accessed 12 December 2017.
Maia RC, de Meis E, Romano S, Dobbin JA, Klumb CE. Rosai-Dorfman disease: a report of eight cases in a tertiary care center and a review of the literature. Braz J Med Biol Res. 2015;48:6-12.
Illing EA, Halum SL. Rosai Dorfman Disease with isolated laryngeal involvement. Ear Nose Throat J 2012;91:439-40.
Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy. Arch Pathol. 1969;87:63 -70.
NORD (National Organization for Rare Disorders). Rosai Dorfman Disease, 2014. Available at: https://rarediseases.org/rare-diseases/rosai-dorfman-disease. Accessed on 12 December 2017.
