Comparative study of benign vocal fold lesions in a tertiary health centre

Geetha K. Siddapur, Kishan R. Siddapur


Background: The present study was carried out to analyze the factors associated with different vocal fold lesions and to diagnose various benign vocal fold lesions at an early stage by their demographic profile and clinical presentations.

Methods: Patients with history of hoarseness of voice as a predominant symptom, cough, pain, foreign body sensation, dryness of throat and with a dominant history of vocal abuse, smoking or alcoholism were included in the study. Patients with acute infections, carcinomas, vocal cord palsy or other neurological diseases were excluded from the study.

Results: The males comprised 66.7% of patients in the study and the commonest age group involved was 30-40 years. Vocal abuse was the leading risk factor in 80% patients. Hoarseness of voice was the predominant symptom in 83% patients followed by vocal fatigue. Bilateral vocal fold involvement was seen in 50% of the cases. All vocal nodule cases had bilateral vocal fold involvement. The vocal nodules were the commonest lesion seen (35%). Intra-operative and post-operative use of intravenous steroids was also found beneficial. Statistical analysis was done using Chi-square test. Significance level was assessed with P value <0.05. The bilateral involvement in all the vocal nodule cases was found significant.

Conclusions: Voice therapy and cessation of smoking and alcohol can significantly reduce the incidence of these benign vocal fold lesions. It’s not only surgery that’s important in managing vocal fold lesions, but the post-operative care equally plays a vital role.


Otorhinolaryngology, Benign, Vocal, Hoarseness, Dysphonia

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Altman KW. Vocal fold masses. Otolaryngol Clin North Am. 2007;40(5):1091-108.

Thomas C, Mona A. The Hoarseness patient. ENT Secrets. 2005;3:179.

Maran AD. Voice problems in Logan Turners disease of ENT. Laryngology. 1982;1:372.

Cohen SM. Prevalence and causes of dysphonia in a large treatment‐seeking population. The Laryngoscope. 2012;122(2):343-8.

Robert W. Bastian. Benign vocal fold mucosal disorders. Cummings Otolaryngol Head Neck Surg. 2005;4(3):2150.

Brodnitz FS. Goals, results and limitations of vocal rehabilitation. Arch Otolaryngol. 1963;77:148-56.

Kleinsasser O. Pathogenesis of vocal cord polyps. An Otol Rhinol Laryngol. 1982;91:378-81.

Mahesh C, Panduranga KM, Kiran B, Ranjith P, Ravi BP. Benign lesions of larynx-a clinical study. Indian J Otolaryngol Head Neck Surg. 2012;57:35-8.

Kotby MN, Nassar AM, Seif EI, Helal EH, Saleh MM. Ultrastructural features of vocal fold nodules and polyps. Acta Otolaryngol. 1988;105:477-82.

Kambic V, Radsel Z, Zarqi M, Acko M. Vocal cord polyps: incidence, histology and pathogenesis. J Laryngol Otol. 1981;95:609-18.

Chopra H, Kapoor M. Study of benign glottic lesions undergoing microlaryngeal surgery. Indian J Otolaryngol Head Neck Surg. 1997;49:276-9.

Ormseth EJ, Wong RK. Reflux laryngitis: Pathophysiology, diagnosis, and management. Am J Gastroentrol. 1999;94:2812-7.

Harding SM, Richter JE. The role of gastroesophageal reflux in chronic cough and asthma. Chest. 1997;111:1389-402.

Shohet JA, Courey MS, Scott MA, Ossoff RH. Value of videostroboscopic parameters in differentiating true vocal fold cysts from polyps. Laryngoscope. 1996;106:19-26.