Bacteriological study and antibiotic sensitivity profile in patients with ear discharge visiting ENT OPD at tertiary care center
Keywords:Chronic suppurative otitis media, Ear discharge, sensitivity
Background: Otitis media (OM) is a big menace in countries like India. Chronic suppurative otitis media (CSOM) is chronic inflammation of middle ear, which affects the tympanic membrane, middle ear mucosa and other middle ear structures characterised by the presence of persistent perforation or persistent mucoid or muco-purulent discharge for at least 8 weeks. Variety of organisms founds in patients suffering from chronic otitis media like, Pseudomonas, Staphylococcus aureus, Proteus mirabilis, Klebsiella pneumonia and Escherichia coli found. The pattern of organisms varies in different geographical areas. The objectives of the study were to isolate bacteria from patients with ear discharge, to find out antibiotic sensitivity of isolated organisms
Methods: This is an observational cross sectional study done in the OPD department of otorhinolaryngology, at P.D.U medical college and hospital, Rajkot, for a period of six months from January 2017 to June 2017. A total number 200 patients of both gender between 5 to 74 years who visited the OPD department of otorhinolaryngology with chronic ear discharge taken for study.
Results: Out of 200 patients of 5-74 years with chronic suppurative otitis media were examined and out of this Hundred and twelve (54%) of the patients were males with mean age of 33.44. Pseudomonas aeruginosa was the commonest identified organisms the sensitivity pattern highly favoured Pipercillin, Amikacin and Polymyxin B, Cefoparazone.
Conclusions: Chronic otitis media is more prevalent in males than females. Commonest organisms found were Pseudomonas aeruginosa followed by Staphylococcus aureus. Piperacillin, Amikacin, Gentamicin, Polymyxin B and Cefoperazone were found most effective agents against Pseudomonas aeruginosa.
El-Gendy GD. The incidence of otitis media with effusion in Menoufiya school children. MD Thesis, Faculty of Medicine, Menoufiya University, 1998.
St Sauver J, Marrs CF, Foxman B, Somsel P, Madera R, Gilsdorf JR. Risk factors for otitis media and carriage of multiple strains of Haemophilus influenzae and streptococcus pneumoniae. Emerg Infect Dis. 2000;6(6):622-30.
B Iqbal J, Khan W, Raza SN, Naqvi NU, Rahat ZM, Azeem QE. Frequency of chronic suppurative otitis media in the junior ranks of Pak army. Pak Armed Forces Med J. 2009;59:367-70.
Brook I, Frazier E. Microbial dynamics of persistent purulent otitis media in children. J Pediatrics. 1996;128:237-40.
John AF. Chronic otitis media: diagnosis and treatment. Med Clin North America. 1991;75:1277-91.
Hatcher J, Smith A, Mackenzie I. A prevalence study of ear problem in school children in Kiambi district, Kenya. Int J Paediatric. Otorhinolaryngol. 1995;33:197-201.
Acuin J, Chronic suppurative otitis media, burden of illness and management options. World Health Organization, Geneva, Switzerland. 2004;1:17.
Wright A. Anatomy and ultrastructure of the human ear, Scott-Brown’s otolaryngology, Basic science sixth edition; Booth JBand Kerr AG,(eds) London, Butterworth-Heinemann. 1997:1/1/7-1/1/26.
Fliss DM, Dagan R, Meidan N, Leiberman A. Aerobic bacteriology of chronic suppurative otitis media without cholesteotoma in children. Ann Otol Rhinol Laryngol. 1992;101:866-9.
Iqbal K, Khan M, Satti L. Microbiology of Chronic Suppurative Otitis Media: Experience at Dera Ismail Khan, Gomal J Med Sci. 2011;9(2):189-93.
Scott brown textbook of otorhinolaryngology 7th 3410-3424.
Nwabuisi C, Ologe FE. Pathogenic agents of Chronic Suppurative Otitis Media in Ilorin, Nigeria. East Afr Med J. 2002;79(4):202-5.
Kumar H, Seth S. Bacterial and Fungal Study of 100 cases of Chronic Suppurative Otitis Media. J Clin Diagnos Res. 2011;5(6):1224-7.
Loy Att, Tan AL, Lee PK, Microbiology of Chronic suppurative otitis media in Singapore. Singapore Med J. 2002;43:296-9.
Nikakhalgh S, Khosravi AD, Fazlipur A, Zadeh MS Rashidi N. Microbiological findings in patients over Chronic suppurative otitis media. J Med Sci. 2008;8:503-33.
Khanna V, Chender J, Nagarkar NM, Dass A. Clinico Microbiologic Evaluation of Active Tubo-tympanic type Chronis suppurative otitis Media. J Otolaryngol. 2000;29(3):148-53.
Chaturvedi VM, Grewel BS, Cad MS. Bacterial study of chronic suppurative otitis media in Benghazi Garga. Med J. 1980;6(2):161.
Chakraborty A, Bhattacharjee A, Purkaystha P. Microbiological Profile of chronic suppurative otitis media.Its significance in North east India. Indian J Otol. 2005;11:39-44.
Taneja MK. Chronic suppurative otitis media. A Bacteriological Study, Indian J Otol. 1995;1(2):24-7.
Mansoor T, Musani M, Khalid G, Kamal M. Pseudomonas aeruginosa in Chronic Suppurative Otitis Media: Sensitivity Spectrum against various Antibiotics in Karachi. J Ayub Med Coll Abbottabad, 2009;21(2):120-3.
Gulati J, Singh TPL, Bias AS. Study of bacterial flora in chronic suppurative otitis media. Indices J Otolaryngol Head Neck Surg. 1969;2:198-202.
Kulkurani RD, Dharmadhikani CA, Kulkarini VA, Udaganokar US, Paver G Gu. Bacteriological study of chronic otitis media. Indian J Otolaryngol Head Neck Surgery. 1993;4(2):110-2.
Zaida H, Abdulla EN. Incidence of potential pathogen in microbial infection in Benghazi and an antibiotic policy. Garyounis Med J. 1979;2(2):27.