Laryngeal mucormycosis: a rare entity
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20175642Keywords:
Laryngeal mucormycosis, Dyspnoea, MucoralesAbstract
"Mucormycosis" term is used in context to a group of fungal diseases caused by the order mucorales. Typically with predilection for the pulmonary and the sino-nasal-orbital tissues, it can very rarely affect the laryngeal as well as the tracheal mucosa either as skip lesions or in continuity. The management of such an involved airway is quite challenging. Literature documents sporadic cases of laryngeal manifestation of mucormycosis. Reported here is such a case of a diabetic male presenting with dyspnoea of sudden onset. Video laryngoscopy revealed extensive glottic edema with a reduced glottis chink. Elective prophylactic tracheostomy followed by direct laryngeal trucut biopsy was undertaken. Histopathology was suggestive of mucormycosis and the patient was administered titrated intravenous Amphoterecin B. The response was favorable and the patient at present is symptom free.
References
Hilal AA. Rhinoorbital mucormycosis secondary to Rhizopus oryzae: a case report and literature review. Ear Nose Throat J. 2004;83(8):556, 558-60, 562.
Avaliable at: http://emedicine.medscape.com/ article/222551-overview#a5. Accessed on 3 August 2017.
Laryngotracheal mucormycosis: Report of a case. Mattioni J Ear Nose Throat J. 2016;95(1):29-39.
Andrews D, Andrew A. Tracheal Mucormycosis. Annals Thoracic Surg. 1997;63(1):230–2.
Spellberg B, Edwards J, Ibrahim A. Novel Perspectives on Mucormycosis: Pathophysiology, Presentation, and Management. Clin Microbiol Rev. 2005;18(3):556-69.
Ellie JC, Walsh J. Recent Advances in the Management of Mucormycosis: From Bench to Bedside. Clin Infect Dis. 2009;48(12):1743-51.
Fernando P, Della M. Histoplasmosis of the Larynx. Revista Brasileira de Otorrinolaringologia. 2007;73(6):857-61.