DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20175612

Treatment outcome of postoperative radiotherapy for squamous cell carcinoma of the head and neck

H. U. Ghori, M. Sohaib, Vivek Tiwari, Manish Ahirwar

Abstract


Background: Though early stage malignancy of head and neck can be cured by surgery or radiotherapy, cure of patients with locally advanced disease continues to pose a therapeutic challenge. Loco regional failure is the major cause of death in head and neck cancer. As the cure of locally advance head and neck cancer is less than expectation, a combined modality approach is generally used in these type of patients. The combination of surgery, radiotherapy and chemotherapy can improve outcome in locally advance head and neck cancer.

Methods: This observational study reviewed cancer patients reported in our hospital with the following inclusion criteria: primary head and neck cancer, treatment with radical surgery, and multiple nodal metastases. The prescribed dose of postoperative radiotherapy was 60–66 Gy. Patient characteristics, treatment parameters and clinical outcome were recorded.  

Results: The primary end point was overall survival, and the secondary endpoint was disease status.

Conclusions: Concurrent postoperative administration of chemotherapy and radiotherapy is a way to intensify treatment for resectable high-risk head and neck tumors.


Keywords


Head and neck cancer, Postoperative, Radiotherapy, Concomitant, Cisplatin

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