Awake airway management for retrograde injection laryngoplasty in a high-risk oncologic patient with severe trismus: a case report

Authors

  • Anand Murugesan Department of Anaesthesia and Pain Medicine, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India
  • Srikanth Tanjore Department of Anaesthesia and Pain Medicine, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India
  • Prethiv Raj Mohan Department of Anaesthesia and Pain Medicine, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India
  • Shrinidhi Ramalingam Department of Anaesthesia and Pain Medicine, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India
  • Sivakumar Vidhyadharan Department of Head and Neck Onco-Surgery, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India
  • Sandip Duarah Department of Head and Neck Onco-Surgery, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India
  • Janakan Sennava Perumal Department of Head and Neck Onco-Surgery, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India
  • Naveen Hedne Department of Head and Neck Onco-Surgery, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20261483

Keywords:

Trismus, Carcinoma tonsil, Retrograde injection, Larynogoplasty, Regional anaesthesia, Conscious sedation

Abstract

Advanced head and neck malignancies often present with complex airway and systemic challenges that critically influence anesthetic management. We report a high-risk patient with carcinoma of the tonsil and widespread metastases who had a prior history of pseudoaneurysm rupture of facial artery treated with embolization, complicated by intra-procedural cardiac arrest, atrial fibrillation, and subsequent dialysis-dependent acute renal failure. The patient later presented with unilateral vocal cord palsy requiring injection laryngoplasty. Severe trismus, compromised pulmonary reserve due to metastatic disease, and underlying cardiac dysfunction rendered general anesthesia particularly hazardous. An awake airway approach using 4% lignocaine nebulization, trans-tracheal block, and dexmeditomidine sedation was employed to maintain spontaneous ventilation while providing optimal procedural conditions. This enabled successful completion of the shared airway procedure using a retrograde technique without complications. This case highlights the importance of individualized anesthetic strategies in high-risk oncologic patients and underscores the value of regional airway anesthesia combined with conscious sedation as a safe alternative to general anesthesia.

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References

University of Iowa, Carver College of Medicine. Injection laryngoplasty for vocal fold paralysis and glottic incompetence. Iowa Head and Neck Protocols. Iowa City (IA): University of Iowa. 2026. Available at: https://iowaprotocols.medicine.uiowa. edu/protocols/injection-laryngoplasty-vocal-fold-paralysis-and-glottic-incompetence. Accessed on 07 March 2026.

Patel A. The shared airway. Curr Anaesth Crit Care. 2001;12(4):213-7. DOI: https://doi.org/10.1054/cacc.2001.0352

Williamson AJ, Mullangi S, Gajra A. Tonsil cancer. In: StatPearls. Treasure Island (FL): StatPearls Publishing. 2026.

Tujjar O, Mineo G, Dell’Anna A, Poyatos-Robles B, Donadello K, Scolletta S, et al. Acute kidney injury after cardiac arrest. Crit Care. 2015;19:169. DOI: https://doi.org/10.1186/s13054-015-0900-2

Duggappa DR, Rao GV, Kannan S. Anaesthesia for patient with chronic obstructive pulmonary disease. Indian J Anaesth. 2015;59(9):574-83. DOI: https://doi.org/10.4103/0019-5049.165859

Law JA, Broemling N, Cooper RM, Drolet P, Duggan LV, Griesdale DE, et al. Management of the anticipated difficult airway-a systematic approach: continuing professional development. Can J Anaesth. 2013;60(12):1069-93.

Robson A, Sturman J, Williamson P, Conboy P, Penney S, Wood H. Pre-treatment clinical assessment in head and neck cancer: United Kingdom National Multidisciplinary Guidelines. J Laryngol Otol. 2016;130(2):S13-22. DOI: https://doi.org/10.1017/S0022215116000372

Pani N, Rath SK. Regional and topical anaesthesia of upper airways. Indian J Anaesth. 2009;53(6):641-8.

Bista A, Goswami D, Rewari V, Khanna P, Pandey RK, Singh CA. Fentanyl versus dexmedetomidine infusion in head and neck free flap surgery for comparison of hemodynamic parameters and anaesthetic requirements: a randomised controlled trial. Indian J Otolaryngol Head Neck Surg. 2024;76(5):4528-36. DOI: https://doi.org/10.1007/s12070-024-04905-3

Ananthapadmanabhan S, Kudpaje A, Raju D, Smith M, Riffat F, Novakovic D, et al. Trans-nasal humidified rapid insufflation ventilatory exchange (THRIVE) and its utility in otolaryngology, head and neck surgery: literature review. Indian J Otolaryngol Head Neck Surg. 2024;76(2):1921-30. DOI: https://doi.org/10.1007/s12070-023-04445-2

Ismail TI, Mahrous RSS, Elbardan IM. The use of a FROVA airway intubation introducer as a guide before nasotracheal intubation could improve insertion condition. Trends Anaesth Crit Care. 2024;57:101375. DOI: https://doi.org/10.1016/j.tacc.2024.101375

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Published

2026-05-18

How to Cite

Murugesan, A., Tanjore, S., Mohan, P. R., Ramalingam, S., Vidhyadharan, S., Duarah, S., Perumal, J. S., & Hedne, N. (2026). Awake airway management for retrograde injection laryngoplasty in a high-risk oncologic patient with severe trismus: a case report. International Journal of Otorhinolaryngology and Head and Neck Surgery. https://doi.org/10.18203/issn.2454-5929.ijohns20261483

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Section

Case Reports