Use of trans-nasal humidified rapid insufflation ventilatory exchange in a post-pneumonectomy patient undergoing injection laryngoplasty: a case report
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20261061Keywords:
THRIVE, Pneumonectomy, Injection laryngoplasty, Unilateral vocal cord paralysis, Shared airway anesthesia, Apneic oxygenationAbstract
Post-pneumonectomy patients present significant anesthetic challenges because of severely reduced pulmonary reserve, altered ventilation-perfusion relationships, and limited tolerance to apnea. Airway procedures requiring a shared field further complicate management. We describe the perioperative management of a 40 years old patient with prior left pneumonectomy who presented with hoarseness of voice secondary to left recurrent laryngeal nerve palsy caused by tumor encasement. The patient underwent injection laryngoplasty using filler material under general anesthesia with trans-nasal humidified rapid insufflation ventilatory exchange (THRIVE) as the primary oxygenation strategy. THRIVE provided effective oxygenation, a tubeless surgical field, and avoidance of positive pressure ventilation in a single-lung patient. This report highlights the physiological considerations in post-pneumonectomy patients and discusses the advantages and limitations of THRIVE compared with microlaryngeal tube ventilation, jet ventilation, and conventional apneic oxygenation.
Metrics
References
Christodoulides N, Fitzmaurice GJ, Bukowska I, O’Rhaillaigh E, Toale C, Griffin M, et al. Post-pneumonectomy syndrome: a systematic review of the current evidence and treatment options. J Cardiothorac Surg. 2023;18:119. DOI: https://doi.org/10.1186/s13019-023-02278-2
Physiologic consequences of pneumonectomy-Batirel-Shanghai Chest. Available at: https://shc.amegroups.org/article/view/6062/html. Accessed on 26 March 2026.
Deslauriers J, Ugalde P, Miro S, Ferland S, Bergeron S, Lacasse Y, et al. Adjustments in cardiorespiratory function after pneumonectomy: Results of the pneumonectomy project. J Thorac Cardiovasc Surg. 2011;141(1):7-15. DOI: https://doi.org/10.1016/j.jtcvs.2010.09.010
Gullung JL, Halstead LA. Recurrent laryngeal nerve paresis postpneumonectomy contralateral to site of surgery. Ann Thorac Surg. 2012;94(2):628-30. DOI: https://doi.org/10.1016/j.athoracsur.2012.01.019
Injection Laryngoplasty for Vocal Fold Paralysis and Glottic Incompetence. Iowa Head and Neck Protocols-Carver College of Medicine. The University of Iowa. Available at: https://iowaprotocols.medicine.uiowa.edu/protocols/injection-laryngoplasty-vocal-fold-paralysis-and-glottic-incompetence. Accessed on 26 March 2026.
Hackett S, Jones R, Kapila R. Anaesthesia for pneumonectomy. BJA Educ. 2019;19(9):297-304. DOI: https://doi.org/10.1016/j.bjae.2019.04.004
Luzzi L, Tenconi S, Voltolini L, Paladini P, Ghiribelli C, Di Bisceglie M, et al. Long-term respiratory functional results after pneumonectomy. Eur J Cardiothorac Surg. 2008;34(1):164-8. DOI: https://doi.org/10.1016/j.ejcts.2008.03.064
Brown LM, Rannels SR, Rannels DE. Implications of post-pneumonectomy compensatory lung growth in pulmonary physiology and disease. Respir Res. 2001;2(6):340-7. DOI: https://doi.org/10.1186/rr84
Evaluation of Pulmonary Blood Flow, Right Atrium, Right Ventricle, and Pulmonary Artery in Patients After Pneumonectomy. Available at: https://www.mdpi.com/2077-0383/14/19/6793. Accessed on 26 March 2026. DOI: https://doi.org/10.3390/jcm14196793
Lau J, Loizou P, Riffat F, Stokan M, Palme CE. The use of THRIVE in otolaryngology: our experiences in two Australian tertiary facilities. Aust J Otolaryngol. 2019;2:22. DOI: https://doi.org/10.21037/ajo.2019.07.02
Jagannathan N. Use of THRIVE in children for head and neck procedures: why is it a useful technique? J Head Neck Anesth. 2020;4(1):e23. DOI: https://doi.org/10.1097/HN9.0000000000000023
Jet Ventilation-an overview. ScienceDirect Topics. Available at: https://www.sciencedirect.com/topics/medicine-and-dentistry/jet-ventilation. Accessed on 26 March 2026.
Mittimanj K, Jabanathan M, Chandrashekhar S, Tandon S. THRIVE: a different approach in microlaryngeal surgeries. Int J Otorhinolaryngol Head Neck Surg. 2022;8(8):672-6. DOI: https://doi.org/10.18203/issn.2454-5929.ijohns20221831
ENT and Audiology News. The use of THRIVE in laryngology and phonosurgery. Available at: https://www.entandaudiologynews.com/development/spotlight-on-innovation/post/the-use-of-thrive-in-laryngology-and-phonosurgery. Accessed on 26 March 2026.
Winerman I, Ezra S, Man A, Segal S. Limitations of jet ventilation through the laryngoscope. Can Anaesth Soc J. 1982;29(2):117-20. DOI: https://doi.org/10.1007/BF03007988