The great mimicker: a case of neck pilomatricoma masked as submandibular gland

Authors

  • Khairullah B. Anuar Department of Otorhinolaryngology, Faculty of Medicine and Health Sciences Universiti Sains Islam Malaysia, Nilai Negeri Sembilan, Malaysia https://orcid.org/0000-0003-0406-6990

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20261511

Keywords:

Lateral neck swelling, Pilomatricoma, Benign skin tumour

Abstract

Lateral neck swelling is common in general population usually it could be from the salivary gland mass namely parotid or submandibular gland. It could also be cervical lymphadenopathy. However, in this case a rare finding was discovered.  We report a case of a 12-year-old boy presented with right cervical neck swelling which increase in size over the past 4 weeks and associated with pain. Clinically it measures 2×2 cm located at right lower cheek close to submandibular gland region.  Excision biopsy was performed. The microscopic description showed multiple pieces of tissue, many are composed of basaloid cells that show abrupt keratinisation without granular layer into ghost cell. Other pieces show multinucleated giant cell of foreign body type reaction. The final diagnosis is pilomatricoma. This is a benign skin tumour derived from the hair matric. It is relatively uncommon and typically occur on the scalp, face and upper extremities. Although it rare to occur at the submandibular region medical professional should be alert and aware that one of the differential diagnoses for the subcutaneous lateral neck mass could be a pilomatricoma.

References

Gleeson M. Regular review: Management of lateral neck masses in adults. BMJ. 2000;20(7248):1521-4.

Tan E, Jaya J. An approach to neck masses in adults. Australia J General Pract. 2020;49(5):267270.

Melloni-Magnelli LF, González-Gaytán D, Sepulveda-Valenzuela M, Peña-Jiménez CY, Martínez-Leija H, Villarreal EG. Pediatric Pilomatrixomas: Four Atypical Clinical Presentations. Plast Surg (Oakv). 2025;33(1):133-8.

Ciucă EM, Sălan AI, Camen A, Matei M, Şarlă CG, Mărgăritescu C. A patient with pilomatricoma in the parotid region: case report and review of the literature. Rom J Morphol Embryol. 2018;59(3):917-26.

Brockschmidt C, Lümkemann N, Diederichs S. Pilomatricoma as a cutaneous manifestation of Gardner’s syndrome: A case report and review of the literature. J Clin Dermatol. 2021;38(2):263-8.

González RA, Martínez MI, Díaz MF. Pilomatricoma: An overview of clinical features, diagnosis, and management. Int J Dermatol. 2021;60(1):7-13.

Kaddu S, Soyer HP, Hödl S, Kerl H. Morphological stages of pilomatricoma. Am J Dermatopathol. 1996;18(4):333-8.

Miao M, Liu F, Zhang C. Pilomatricoma: A rare, benign skin neoplasm with clinical and histopathologic correlations. Arch Dermatol Res. 2020;312(4):247-53.

Ranjan D, Bhat MM, Sood A. Pilomatricoma: Diagnosis and management. Indian J Dermatol. 2020;65(5):388-92.

Tate J, Patel S, Thompson J. Pilomatricoma: A benign tumor with diagnostic and management implications. J Am Acad Dermatol. 2020;83(6):1521-4.

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Published

2026-05-25

How to Cite

Anuar, K. B. (2026). The great mimicker: a case of neck pilomatricoma masked as submandibular gland . International Journal of Otorhinolaryngology and Head and Neck Surgery, 12(3), 425–427. https://doi.org/10.18203/issn.2454-5929.ijohns20261511

Issue

Section

Case Reports