Pleomorphic adenoma of the hard palate: a case report

Authors

  • Yeseera Alavudeen Department of ENT, Indira Gandhi Government General Hospital and Post Graduate Institute, Puducherry, India
  • Stalin Sivagurunathan Department of ENT, Indira Gandhi Government General Hospital and Post Graduate Institute, Puducherry, India
  • Shailaja Mathivanan Department of ENT, Indira Gandhi Government General Hospital and Post Graduate Institute, Puducherry, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20263400

Keywords:

Pleomorphic adenoma, Hard palate, Minor salivary gland tumor, Wide local excision, Histopathology, Case report

Abstract

Pleomorphic adenoma is the most common benign salivary gland tumor. It is a mixed tumor composed of epithelial and myoepithelial cells arranged in various morphological patterns and is usually demarcated by a fibrous capsule from surrounding tissues. While it commonly affects major salivary glands, its occurrence in minor salivary glands is less frequent. It shows a female predominance (60%) compared to males (40%). We report a case of a 45-year-old male patient, a driver by occupation, with a history of smoking, alcohol intake, and tobacco chewing for 25 years. He presented with a painless swelling over the hard palate for the past 2 years. Clinical examination and investigations led to a provisional diagnosis of pleomorphic adenoma of the minor salivary glands of the hard palate. The lesion was treated with wide local excision under local anesthesia. The excised specimen was sent for histopathological examination for definitive diagnosis. Histopathological examination confirmed the diagnosis of pleomorphic adenoma. The patient had an uneventful postoperative recovery with good healing. The palatal defect was allowed to heal by secondary intention, and satisfactory granulation with complete healing was observed. Pleomorphic adenoma of the minor salivary glands of the hard palate is a relatively rare entity but carries an excellent prognosis when treated with wide local excision. Definitive diagnosis depends on histopathological evaluation. Early diagnosis and adequate surgical management ensure good functional and cosmetic outcomes.

References

Tamba B, Diatta M, Kane M, Lo B, Ba A, Tine SD. Management of a giant pleomorphic adenoma of the palate: case report. Adv Oral Maxillofac Surg. 2021;4:100168.

Tallini G, Asa SL. RET gene rearrangements and other genetic drivers in salivary gland tumors. Endocr Pathol. 2020;31(1):112-23.

Barnes L, Eveson JW, Reichart P, Sidransky D, editors. Pathology and genetics of head and neck tumours. Lyon (France): IARC Press; 2005.

Speight PM, Barrett AW. Salivary gland tumours. Oral Dis. 2002;8(5):229-40.

Regezi JA, Sciubba JJ, Jordan RCK. Oral pathology: clinical pathologic correlations. 6th ed. St. Louis (MO): Elsevier Saunders; 2012.

Goyal G, Singh P, Dey P. Cytology of pleomorphic adenoma: a study of 70 cases. J Cytol. 2017;34(4):185-9.

Ogata DC, Costa FG, Ribeiro-Silva A, Fregnani ER. Clinicopathological and immunohistochemical analysis of pleomorphic adenoma and carcinoma ex pleomorphic adenoma of the salivary glands. Med Oral Patol Oral Cir Bucal. 2018;23(3):e342-9.

Fernandes GC, Pandya KA. Pleomorphic adenoma of the hard palate: a case report. J Dent Med Sci. 2015;14(6):90-3.

Chauhan S, Parashar P, Sharma K. Management of recurrent pleomorphic adenoma: a case report. J Maxillofac Oral Surg. 2019;18(1):155-9.

Menon G, Winters R. Pleomorphic Adenoma. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025.

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Published

2026-09-25

How to Cite

Alavudeen, Y., Sivagurunathan, S., & Mathivanan, S. (2026). Pleomorphic adenoma of the hard palate: a case report . International Journal of Otorhinolaryngology and Head and Neck Surgery, 12(5), 836–839. https://doi.org/10.18203/issn.2454-5929.ijohns20263400