Myriad manifestations of parathyroid adenoma – clinical insights from a case series

Thushara K.; Dathathri H. A.

doi:10.18203/issn.2454-5929.ijohns20261504

Authors

Thushara K. Department of ENT, Manipal Hospital, Mysore, Karnataka, India
Dathathri H. A. Department of ENT, Manipal Hospital, Mysore, Karnataka, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20261504

Keywords:

Parathyroid, Hypercalcemia, Hyperparathyroidism, Scintigraphy, Parathyroid adenoma, Pephrocalcinosis

Abstract

Parathyroid adenoma is the most common cause of primary hyperparathyroidism and demonstrates a wide spectrum of clinical manifestations, ranging from asymptomatic hypercalcemia detected on routine evaluation to classical “bones, stones, abdominal groans, and psychic moans”. Biochemical markers along with combined imaging modalities help in arriving at the diagnosis. This case series highlights four different cases with diverse clinical scenarios causing diagnostic challenges and their management. Establishing the diagnosis, accurate preoperative localization followed by timely surgical intervention provides excellent cure rates with minimal morbidity, thereby preventing long term complications and significantly improving patient outcomes.

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