DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20173201

An observational study of benign oral lesions in central India

Prashant N. Keche, Nishikant P. Gadpayle, Surendra H. Gawarle, Gaurav A. Chamania

Abstract


Background: The oral mucosa serves as a protective barrier against trauma, pathogens and carcinogenic agents. It can be affected by a wide variety of lesions and conditions, some of which are harmless while others may have serious complications. The appearance of benign oral soft tissue masses can occasionally resemble malignant tumors.

Methods: Present study is an observational and cross sectional study under taken in the Department of ENT in Shri Vasant Rao Naik Government Medical College, Yavatmal. All cases of benign oral lesions were included in the study and following cases were excluded: malignant oral lesions, immunocompromised state and benign Oral lesions due to systemic diseases.  

Results: Present study included 235 lesions of oral cavity which were clinically or histo-pathologically found to be benign in nature. Benign oral lesions were more commonly found in males with (70.2%) than females (29.8%), and M:F ratio was 2.3:1. most common benign oral lesions were found to be Oral Sub Mucus Fibrosis (26.8%) followed by Apthous ulcers (20.4%), Leukoplakia (18.3%) and Mucocele (17.1%). Least common benign oral lesions were found to be Minor Salivary Gland Tumor (MSGT) (1.7%) followed by Squamous Papilloma (2.1%), Ranula (2.1%) and Hemangioma (2.1). There was a male predominance in oral sub mucus fibrosis with M:F ratio of 9.5:1 followed by Leukoplakia with M:F ratio of 4.4:1. OSMF was found most commonly in 21-30 years age group with (57.1%). Followed by 11-20 years with (20.6%). No cases were found in ≤10 years, 51-60 and >60 years age group.

Conclusions: Most of the benign oral lesions have a predilection to transform into malignant lesions therefore imperative to diagnose the pre malignant lesions of oral cavity in an early stage where appropriate treatment can be given.


Keywords


Pre malignant, Benign, Oral, OSMF, Leukoplakia, Apthous ulcer

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References


Patil S, Doni B, Maheshwari S. Prevalence and Distribution of Oral Mucosal Lesions in a Geriatric Indian Population. Can Geriatr J. 2015;18(1):11-4.

Ali M, Joseph B, Sundaram D. Prevalence of oral mucosal lesions in patients of the Kuwait University Dental Center. Saudi Dent J. 2013;25(3):111-8.

Al-Khateeb TH. Benign oral masses in a Northern Jordanian population-a retrospective study. The open dentistry journal. 2009;3:147-53.

Gupta PC. A study of dose-response relationship between tobacco habits and oral leukoplakia. Br J Cancer. 1984;50(4):527-31.

Coelho KR. Challenges of the oral cancer burden in India. J Cancer Epidemiol. 2012;2012:701932.

Ambekar DM, Chaudhary BJ, Kulkarni VV. A Study of Prevalence of Oral Precancerous Lesions In Relation To Tobacco Habituation. Int J Med Clin Res. 2014;5(1):282.

Chalkoo AH, Ahmad MB. Localized Benign Lesions of Oral Cavity : a Clinicopathological Study of 95 Cases : a Retrospective Analysis 2012-2014. Pakistan Oral Dent J. 2014-15;35(2):179-82.

Mithra N. Hegde RJ, Punja A. Prevalence of oral mucosal lesions and their co -relation to habits in patients visiting a dental school of south karnataka : a cross sectional survey: 2012. Nitte Univ J Health Sci. 2014;4(4):69-72.

Kadeh H, Saravani S, Tajik M. Reactive hyperplastic lesions of the oral cavity. Iranian J Otorhinolaryngol. 2015;27(79):137-44.

Harish SP, Agrawal T, Sajitha K, Bhat SP, Kishan Prasad HL, Srinivas T. A histomorphological study of benign lesions of oral cavity in a tertiary care hospital. J Evol Med Dent Sci. 2015;4(100):16495-8.

Modi D, Laishram R, Sharma L, Debnath K. Pattern of oral cavity lesions in a tertiary care hospital in Manipur, India. J Medical Society. 2013;27(3):199-202.

Bhatnagar P, Rai S, Bhatnagar G, Kaur M, Goel S, Prabhat M. Prevalence study of oral mucosal lesions, mucosal variants, and treatment required for patients reporting to a dental school in North India: In accordance with WHO guidelines. J Family Community Med. 2013;20(1):41-8.

Shahsavari F, Khourkiaee SS, Ghasemi Moridani S. Epidemiologic Study of Benign Soft Tissue Tumors of Oral Cavity in an Iranian Population. J Dentomaxillofacial Radiol Pathol Surg. 2012;1(1):10-5.

Agrawal R, Chauhan A, Kumar P. Spectrum of Oral Lesions in A Tertiary Care Hospital. J Clin Diagnos Res. 2015;9(6):11-3.

Kosam SPK. Pattern of Oral Cavity Lesion: A Retrospective Study of 350 Cases. Int J Sci Study. 2016;4(3):65-9.

Pandya S, Chaudhary AK, Singh M, Singh M, Mehrotra R. Correlation of histopathological diagnosis with habits and clinical findings in oral submucous fibrosis. Head Neck Oncol. 2009;1:10.

Abdullah MJ. Prevalence of recurrent aphthous ulceration experience in patients attending Piramird dental speciality in Sulaimani City. J Clin Experimental Dent. 2013;5(2):89-94.

Mathew AL, Pai KM, Sholapurkar AA, Vengal M. The prevalence of oral mucosal lesions in patients visiting a dental school in Southern India. Indian J Dental Res. 2008;19(2):99-103.

Mishra M, Mohanty J, Sengupta S, Tripathy S. Epidemiological and clinicopathological study of oral leukoplakia. Indian J Dermatol Venereol Leprol. 2005;71(3):161-5.

More CB, Bhavsar K, Varma S, Tailor M. Oral mucocele: A clinical and histopathological study. J Oral Maxillofacial Pathol. 2014;18(1):72-7.

Oliveira DT, Consolaro A, Freitas FJ. Histopathological spectrum of 112 cases of mucocele. Brazilian Dental J. 1993;4(1):29-36.

Corrêa PH, Nunes LCC, Johann ACBR, Aguiar MCFd, Gomez RS, Mesquita RA. Prevalence of oral hemangioma, vascular malformation and varix in a Brazilian population. Brazilian Oral Res. 2007;21:40-45.

Allon I, Kaplan I, Gal G, Chaushu G, Allon DM. The clinical characteristics of benign oral mucosal tumors. Medicina Oral, Patología Oral y Cirugía Bucal. 2014;19(5):438-43.

Torres-Domingo S, Bagan JV, Jiménez Y, Poveda R, Murillo J, Díaz JM, et al. Benign tumors of the oral mucosa: a study of 300 patients. Med Oral Patol Oral Cir Bucal. 2008;13(3):161-6.