Metastatic carotid body tumor: a rare condition
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20260795Keywords:
Metastatic paraganglioma, Gigantic paraganglioma, Carotid body tumorsAbstract
Carotid body tumors (CBTs), or carotid glomus tumors, are rare, slow-growing benign neoplasms arising from the carotid body chemoreceptor. Metastatic disease is uncommon and poorly understood. We report the case of a 53-year-old male with a Shamblin type IIIB CBT, treated with a hybrid approach involving stent placement followed by en bloc resection. He remained disease-free for 116 months before developing regional recurrence along with pulmonary, bone, and brain metastases, which were managed with palliative radiotherapy. The patient died three years after the onset of the first metastases. This case highlights that CBT metastasis may arise more than a decade after initial treatment, underscoring the importance of long-term follow-up and multidisciplinary management.
Metrics
References
Serra R, Grande R, Gallelli L, Rende P, Scarcello E, Buffone G, et al. Carotid body paragangliomas and matrix metalloproteinases. Ann Vasc Surg. 2014;28(7):1665-70. DOI: https://doi.org/10.1016/j.avsg.2014.03.022
Luna-Ortiz K, Rascon-Ortiz M, Villavicencio-Valencia V, Herrera-Gomez A. Does Shamblin's classification predict post-operative morbidity in carotid body tumors? A proposal to modify Shamblin's classification. Eur Arch Otorhinolaryngol. 2006;263(2):171-5. DOI: https://doi.org/10.1007/s00405-005-0968-4
Luna-Ortiz K, Rascon-Ortiz M, Villavicencio-Valencia V, Granados-Garcia M, Herrera-Gomez A. Carotid body tumors: review of a 20-year experience. Oral Oncol. 2005;41(1):56-61. DOI: https://doi.org/10.1016/j.oraloncology.2004.06.006
Fink-Josephi G, Hurtado-López LM, Hernández-Valencia AF, Higuera-Calleja JA, Guerrero-Avendaño G, et al. Two-stage, hybrid endovascular and open surgical approach to treat difficult carotid body tumors. Head Neck. 2022;44(12):2803-9. DOI: https://doi.org/10.1002/hed.27190
Kim GY, Lawrence PF, Moridzadeh RS, Zimmerman K, Munoz A, Luna-Ortiz K, et al. New predictors of complications in carotid body tumor resection. J Vasc Surg. 2017;65(6):1673-9. DOI: https://doi.org/10.1016/j.jvs.2016.12.124
Amato B, Serra R, Fappiano F, Rossi R, Danzi M, Milone M, et al. Surgical complications of carotid body tumors surgery: a review. Int Angiol. 2015;34(6):15-22.
Gür AK, Aykaç MC, Yargı M, Eker E. Complications associated with carotid body tumor excision. Turk Gogus Kalp Damar Cerrahisi Derg. 2018;26(1):81-5. DOI: https://doi.org/10.5606/tgkdc.dergisi.2018.13614
Robertson V, Poli F, Hobson B, Saratzis A, Ross NA. A systematic review and meta-analysis of the presentation and surgical management of patients with carotid body tumours. Eur J Vasc Endovasc Surg. 2019;57(4):477-86. DOI: https://doi.org/10.1016/j.ejvs.2018.10.038
Xing J, Cheng Y, Ying H, Guan M, Jia N, Bai C. Systemic treatment of a metastatic carotid body tumor: a case report and literature review. Medicine (Baltimore). 2020;99(47):e22811. DOI: https://doi.org/10.1097/MD.0000000000022811
Massey V, Wallner K. Treatment of metastatic chemodectoma. Cancer. 1992;69(3):790-2. DOI: https://doi.org/10.1002/1097-0142(19920201)69:3<790::AID-CNCR2820690329>3.0.CO;2-U
Dimakakos PB, Kotsis TE. Carotid body paraganglioma: review and surgical management. Eur J Plast Surg. 2001;24(1):58-65. DOI: https://doi.org/10.1007/s002380100231
Downloads
Published
How to Cite
Issue
Section
