The diagnostic surprise of solitary anaplastic myeloma of mandible: a rare case report

Bala Krishna Vaddepally; Vikas Sharma; Tanuj Madan; Prashanth Sengupta; Dibangkar Das; Zia Zafar

doi:10.18203/issn.2454-5929.ijohns20252263

Authors

Bala Krishna Vaddepally Department of ENT-HNS, Command Hospital Eastern Command, Kolkata, West Bengal, India
Vikas Sharma Department of ENT-HNS, Command Hospital Eastern Command, Kolkata, West Bengal, India
Tanuj Madan Department of ENT-HNS, Command Hospital Eastern Command, Kolkata, West Bengal, India
Prashanth Sengupta Department of Nephropathologist, Command Hospital Eastern Command, Kolkata, West Bengal, India
Dibangkar Das Department of ENT-HNS, Command Hospital Eastern Command, Kolkata, West Bengal, India
Zia Zafar Department of ENT-HNS, Command Hospital Eastern Command, Kolkata, West Bengal, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20252263

Keywords:

Plasma cell neoplasm, Multiple myeloma, Plasmacytoma, Mandible, Jaw swelling

Abstract

Myeloma predominantly affects the elderly who develop a monoclonal protein which is found in their blood and/or urine manifesting as anemia, osteolytic lesions, hypercalcemia, bone pains and renal compromise. Osteolytic lesions are seen in more than 30% of patients with multiple myeloma. However, primary affection of mandible manifest as solitary plasmacytoma of bone occurs in only 4.4% such cases making it a highly unaccustomed entity. The aim of this case report is to present the clinico-pathological profile and the immunohistochemical features of anaplastic myeloma that will be of immense utility in diagnosing its affection of oral cavity and mandible precisely.

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References

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