Epidemiological, clinical and histological profile of oral carcinomas at the Sylvanus Olympio University Hospital in Lome
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20252979Keywords:
Oral cancer, Oral carcinoma, LoméAbstract
Background: Early detection of oral carcinomas is a crucial public health issue. The aim of this study was to describe the epidemiological, clinical and histopathological profile of carcinomas diagnosed in a referral healthcare facility in Lomé
Methods: A retrospective descriptive study was conducted over a period of 10 years, including the medical records of patients presenting with carcinoma of the oral cavity confirmed by anatomopathological examination. Clinical and histopathological socio-demographic parameters were collected and analysed using R software version 4.0.4.
Results: Forty-five (45) cases of carcinoma of the oral cavity were included, with an annual frequency of 4.5 cases. Males predominated with 68.9% of cases. The age group 55 and over was the most affected, with 71.2% of the sample. Alcohol was the most common risk factor (82.2%). The tongue was the preferred site of oral carcinomas with 55.5% and squamous cell carcinoma was the most common histological type.
Conclusions: The carcinoma of the oral cavity in Lomé are predominantly male, in relatively elderly patients with an alcohol-smoking past. While awaiting more in-depth studies on risk factors, raising awareness of the harmful effects of these factors will make it possible to deduce the incidence and morbidity of carcinomas in Togo.
Metrics
References
Zwetyenga N. Les cancers de la cavité buccale: Généralités, épidémiologie, facteurs de risque. EMC- Chirurgie orale et maxillo-faciale. 2024;37(2):1-10. DOI: https://doi.org/10.1016/S2352-3999(25)42092-5
Ferlay J, Colombet M, Soerjomataram I, Mathers C, Parkin DM, Piñeros M, et al. Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods. Int J Cancer. 2019;144(8):1941‑53. DOI: https://doi.org/10.1002/ijc.31937
Lompo-Goumbri OM, Domagni OE, Sanou AM, Konsegré V, Soudré RB. Aspects épidémiologiques et histopathologiques des cancers au Burkina Faso. Journal africain du cancer 2009;1:207-11. DOI: https://doi.org/10.1007/s12558-009-0052-x
Hounkpatin S, Brun L, Balle M-C, Bouraima F, Bossou T, Amegan N, et al. Histo-Epidemiological Profile of Head and Neck Cancers in Benin. Int J Otolaryngol Head Neck Surg. 2020;09(1):19-29. DOI: https://doi.org/10.4236/ijohns.2020.91004
Darre T, Kpatcha TM, Bagny A, Maneh N, Gnandi-Piou F, Tchangai B, et al. Descriptive Epidemiology of Cancers in Togo from 2009 to 2016. Asian Pac J Cancer Prev 2017;18(12):3407-11.
Olson CM, Burda BU, Beil T, Whitlock EP. Screening for Oral Cancer: A Targeted Evidence Update for the U.S. Preventive Services Task Force. Rockville (MD): Agency for Healthcare Research and Quality (US). 2013.
Radhakrishnan R, Shrestha B, Bajrachary D. Oral Cancer - An Overview. Oral Cancer. InTech; 2012;47-64. DOI: https://doi.org/10.5772/30399
Chowdhury RM, Singh G, Joshi A, Singh DK, Bhatia S, Goswami S. Autophagy and oral cancers: A short review. J Stomatol Oral Maxillofac Surg. 2018;119(1):37-9 DOI: https://doi.org/10.1016/j.jormas.2017.11.001
Paré A, Joly A. Cancers de la cavité buccale : facteurs de risque et prise en charge. Presse Med. 2017;46(3):320-30. DOI: https://doi.org/10.1016/j.lpm.2017.01.004
Alonso JE, Kuan EC, Arshi A, St John MA. A population-based analysis of verrucous carcinoma of the oral cavity. Laryngoscope. 2018;128(2):393-7. DOI: https://doi.org/10.1002/lary.26745
Darré T, Walla A, Kpatcha TM, Aboubakari AS, Maneh N, Koulinga M, et al. Cancers in the elderly seen in anatomical pathology laboratory in Lomé, Togo. Open J Pathol. 2016;6:26-31. DOI: https://doi.org/10.4236/ojpathology.2016.61005
D’Elbée JM, Ella B, Fricain JC. Carcinome épidermoïde buccal chez le sujet jeune: présentation d’un cas. Med Buccale Chir Buccale 2013;19:39-43. DOI: https://doi.org/10.1051/mbcb/2012042
Bambara AT, Millogo M, Konsem T, Bambara HA, Ouedraogo D, Traore SS. Les cancers de la cavité buccale: affection à prédominance féminine à Ouagadougou. Medecine Buccale Chirurgie Buccale. 2015;21:61-6. DOI: https://doi.org/10.1051/mbcb/2015011
Adeyemi BF, Olusanya AA, Lawoyin JO. Oral squamous cell carcinoma, socioeconomic status and history of exposure to alcohol and tobacco. J Natl Med Assoc. 2011;103(6):498-502. DOI: https://doi.org/10.1016/S0027-9684(15)30364-3
Eltohami YI, Suleiman AM. Clinical Presentation of Wide Field of Cancerization Associated with Oral Squamous Cell Carcinoma. Int J Dent. 2023;2023:7530295. DOI: https://doi.org/10.1155/2023/7530295
Toure S, Sonko L, Diallo BK, Diop R, Diop A, Diouf R, et al. Profil épidémiologique des cancers de la cavité buccale au Sénégal. Rev de stomatologie et de chirurgie maxillo-faciale. 2005;106(68):43. DOI: https://doi.org/10.1016/S0035-1768(05)86032-2
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209-49. DOI: https://doi.org/10.3322/caac.21660
Muller S, Tilakaratne WM. Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Tumours of the Oral Cavity and Mobile Tongue. Head Neck Pathol. 2022;16(1):54-62. DOI: https://doi.org/10.1007/s12105-021-01402-9
Feller L, Chandran R, Khammissa RA, Meyerov R, Lemmer J. Alcohol and oral squamous cell carcinoma. SADJ. 2013;68(4):176-180.
Rochefort J, Radoi L, Campana F, Fricain JC, Lescaille G Le cancer de la cavité orale : une entité spécifique? Med Sci (Paris).2024;40(1):57-63. DOI: https://doi.org/10.1051/medsci/2023196
Balaram P, Sridhar H, Rajkumar T. Oral cancer in southern India: the influence of smoking, drinking, paanchewing, oral hygiene. Int J Cancer. 2002;98:440-5. DOI: https://doi.org/10.1002/ijc.10200
Barthélémy I, Sannajust J-P, Revol P, Mondié J- M. Cancers de la cavité buccale. Préambule, épidémiologie, étude clinique. EMC-Médecine buccale. 2008;1(4):1-13. DOI: https://doi.org/10.1016/j.emcsto.2005.08.002
Chidzonga MM. Oral malignant neoplasia: a survey of 428 cases in two Zimbabwean hospitals. Oral Oncol. 2006;42(2):177-83. DOI: https://doi.org/10.1016/j.oraloncology.2005.07.003
Amana B, Foma W, Pegbessou E, Bissa H, Adam S, Amana E, et al. Cancers primitifs oto-rhino-laryngologiques et cervico-maxillo-faciaux: aspects épidémiologiques et histopathologiques. Pan Afr Med J. 2016;25:47. DOI: https://doi.org/10.11604/pamj.2016.25.47.9953
Mangione F, Dridi SM, Gaultier F. Carcinome épidermoïde et ulcérations buccales. Réalités Clin. 2016;73:83-90.
Osman TA, Satti AA, Boe OE, Yang YH, Ibrahim SO, Suleiman AM. Pattern of malignant tumors registered at a referral oral and maxillofacial hospital in Sudan during 2006 and 2007. J Cancer Res Ther. 2010;6(4):473-7. DOI: https://doi.org/10.4103/0973-1482.77112
Diabaté K. La radiochimiothérapie dans le traitement des cancers épidermoïdes de la Cavité buccale chez le sujet âgé: à propos d’un cas et revue de la littérature. Rev Col Odonto-Stomatol Afr Chir Maxillo-fac. 2019;26(3):16-9.