A comprehensive case report of kimura’s disease: diagnosis and treatment insights
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20251520Keywords:
Kimura's disease, Lipomatosis, Eosinophilia, Hyperplastic lymphoid folliclesAbstract
Kimura's disease is a rare chronic inflammatory disorder primarily affecting the head and neck region. We present a case of a 35-year-old male patient with swelling over the right preauricular region and right eyebrow for 5 months. The patient's blood investigations revealed elevated eosinophil count, increased absolute eosinophil count, and significantly elevated serum IgE levels. Ultrasonography suggested lipomatosis, while fine-needle aspiration cytology (FNAC) was inconclusive. Excisional biopsy of the swellings confirmed the diagnosis of Kimura's disease based on histopathological findings of hyperplastic lymphoid follicles with micro abscesses. The patient was initiated on intravenous dexamethasone, resulting in a reduction in swelling size and a subsequent decrease in serum IgE levels and eosinophil count. This case report highlights the clinical presentation, diagnostic challenges, and therapeutic response of Kimura's disease.
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Kimura T, Yoshimura S, Ishikawa E. On the unusual granulation combined with hyperplastic changes of lymphatic tissues. Trans Soc Pathol J. 1948;37:179-80.
Dhingra H, Nagpal R, Baliyan A, Alva SR. Kimura disease: case report and brief review of literature. Med Pharm Reports. 2019;92(2):195. DOI: https://doi.org/10.15386/cjmed-1030
Rajesh A, Prasanth T, Sirisha VN, Azmi MD. Kimura’s disease: A case presentation of postauricular swelling. Nigerian J Clin Prac. 2016;19(6):827-30. DOI: https://doi.org/10.4103/1119-3077.164361
Tseng CF, Lin HC, Huang SC, Su CY. Kimura’s disease presenting as bilateral parotid masses. European Arch Otorhinolaryngol Head Neck. 2005;262:8-10. DOI: https://doi.org/10.1007/s00405-003-0677-9
Shetty AK, Beaty MW, McGuirt WF, Woods CR, Givner LB. Kimura’s disease: a diagnostic challenge. Pediatrics. 2002;110(3):39. DOI: https://doi.org/10.1542/peds.110.3.e39
Fouda MA, Gheith O, Refaie A, El-Saeed M, Bakr A, Wafa E. Kimura disease: a case report and review of the literature with a new management protocol. Int J Nephrol. 2011;2:10.
Sato Y, Katsuda S, Kiyoshima K. Pathogenesis of Kimura disease: a clinicopathological review of 21 cases. Pathol Int. 2004;54(10):673-9.
Chen H, Thompson LD, Aguilera NS, Abbondanzo SL. Kimura disease: a clinicopathologic study of 21 cases. Am J Surg Pathol. 2004;28(4):505-13. DOI: https://doi.org/10.1097/00000478-200404000-00010
Alshaibani AK, Al-Mulla AH, Mohammed MA, Alhamoud M, Al-Hassan SA, Alshaibani A, Mohammed M, Al-Hassan S. Isolated kimura disease presenting as a brow mass in a Saudi male: a rare case report. Cureus. 2022;14(3):67. DOI: https://doi.org/10.7759/cureus.23000
Zhao H, Cao ZW, Gu ZW. Case report: a rare case of nasal forehead mass in Kimura's disease. Front Surg. 2021;8:672291. DOI: https://doi.org/10.3389/fsurg.2021.672291
Malhotra M, Varshney S, Singh N, Kumar S. Kimura disease: a rare case report from Himalayan Region. Indian J Otolaryngol Head Neck Surg. 2017;69:571-4. DOI: https://doi.org/10.1007/s12070-016-1045-6
Qureshi TA, Siddiqui MI, Tariq MU. Kimura’s disease of head and neck: a rare case presentation. Egyptian J Otolaryngol. 2015;31:73-5. DOI: https://doi.org/10.4103/1012-5574.152713
Meningaud JP, Pitak-Arnnop P, Fouret P, Bertrand JC. Kimura’s disease of the parotid region: report of 2 cases and review of the literature. J Oral Maxillofac Surg. 2007;65:134-40. DOI: https://doi.org/10.1016/j.joms.2005.10.043
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