Biofilm in cochlear implantation: our experience
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20251513Keywords:
Biofilm, Cochlear implant, ComplicationsAbstract
Bacterial biofilm formation on cochlear implant leads to intractable infections. Though rare, it is one of the most dreaded complications which leads to explantation in most of the cases. 400 consecutive cases of cochlear implantation done at tertiary care center over a period of 7 years included. Treatment protocol followed in Biofilm and results are discussed in our case report. Two cases of biofilm where one implant could be successfully salvaged whereas other needed explantation of the implant. There is no universally accepted standardized treatment for this complication. Salvage surgery can be attempted before explantation.
Metrics
References
Cunningham III CD, Slattery III WH, Luxford WM. Postoperative infection in cochlear implant patients. Otolaryngol Head Neck Surg. 2004;131(1):109-14. DOI: https://doi.org/10.1016/j.otohns.2004.02.011
Cohen NL, Hoffman RA. Complications of cochlear implant surgery in adults and children. Ann Otol Rhinol Laryngol. 1991;100(9):708-11. DOI: https://doi.org/10.1177/000348949110000903
Brady A, Loughlin R, Gilpin D, Kearney P, Tunney M. In vitro activity of tea-tree oil against clinical skin isolates of meticillin-resistant and-sensitive Staphylococcus aureus and coagulase-negative staphylococci growing planktonically and as biofilms. J Med Microbiol. 2006;55(10):1375-80. DOI: https://doi.org/10.1099/jmm.0.46558-0
Karatan E, Watnik P. Signals, regulatory networks, and materials that build and break bacterial biofilms. Microbiol Mol Biol Rev. 2009;73:310-47. DOI: https://doi.org/10.1128/MMBR.00041-08
Federle MJ, Bassler BL. Interspecies communication in bacteria. J Clin Invest. 2003;112:1291-9. DOI: https://doi.org/10.1172/JCI200320195
Konig DP, Schierholz JM, Munnich U, Rutt J. Treatment of staphylococcal implant infection with rifampicin-ciprofloxacin in stable implants. Arch Orthop Trauma Surg. 2001;121:297-9. DOI: https://doi.org/10.1007/s004020000242
Brady AJ, Farnan TB, Toner JG, Gilpin DF, Tunney MM. Treatment of a cochlear implant biofilm infection: a potential role for alternative antimicrobial agents. J Laryngol Otol. 2010;124(7):729. DOI: https://doi.org/10.1017/S0022215110000319
Kabelka Z, Groh D, Katra R, Jurovcik M. Bacterial infection complications in children with cochlear implants in the Czech Republic. Int J Pediatr Otorhinolaryngol. 2010;74(5):499-502. DOI: https://doi.org/10.1016/j.ijporl.2010.02.007
Germiller JA, El-Kashlan HK, Shah UK. Chronic Pseudomonas infections of cochlear implants. Otol Neurotol. 2005;26(2):196-201. DOI: https://doi.org/10.1097/00129492-200503000-00011
Vaid N, Vaid S, Manikoth M. Case report–biofilm infection of a cochlear implant. Cochlear Implants Int. 2013;14(2):117-20. DOI: https://doi.org/10.1179/1754762811Y.0000000025
Yu KC, Hegarty JL, Gantz BJ, Lalwani AK. Conservative management of infections in cochlear implant recipients. Otolaryngol Head Neck Surg. 2001;125(1):66-70. DOI: https://doi.org/10.1067/mhn.2001.116444
Gawęcki W, Karlik M, Borucki Ł, Szyfter-Harris J, Wróbel M. Skin flap complications after cochlear implantations. Eur Arch Oto-rhino-laryngol. 2016;273:4175-83. DOI: https://doi.org/10.1007/s00405-016-4107-1
Sharma S, Gupta A, Bhatia K, Lahiri AK, Singh S. Salvaging cochlear implant after wound infection: Well worth a try. Cochlear Implants Int. 2017;18(4):230-4. DOI: https://doi.org/10.1080/14670100.2017.1321299
Suri N, Yadav C, Sandilya S, Bhalodia N. Salvaging Cochlear Implant After Suspected Biofilm Infection: Our Experience. Indian J Otolaryngol Head Neck Surg. 2021;73(4):499-503. DOI: https://doi.org/10.1007/s12070-021-02627-4
Monzón M, Oteiza C, Leiva J, Lamata M, Amorena B. Biofilm testing of Staphylococcus epidermidis clinical isolates: low performance of vancomycin in relation to other antibiotics. Diagnost Microbiol Infect Dis. 2002;44(4):319-24. DOI: https://doi.org/10.1016/S0732-8893(02)00464-9
Toté K, Berghe DV, Deschacht M, De Wit K, Maes L, Cos P. Inhibitory efficacy of various antibiotics on matrix and viable mass of Staphylococcus aureus and Pseudomonas aeruginosa biofilms. Int J Antimicrob Agents. 2009;33(6):525-31. DOI: https://doi.org/10.1016/j.ijantimicag.2008.11.004
Saginur R, StDenis M, Ferris W, Aaron SD, Chan F, Lee C, et al. Multiple combination bactericidal testing of staphylococcal biofilms from implant-associated infections. Antimicrob Agents Chemother. 2006;50(1):55-61. DOI: https://doi.org/10.1128/AAC.50.1.55-61.2006
Downloads
Published
How to Cite
Issue
Section
