An incongruous occurrence: rare case of a huge sinonasal neurofibroma
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20243520Keywords:
Sinonasal neurofibroma, Nasal rumours, Lateral rhinotomy, Nasal massesAbstract
Neurofibromas (NF) are benign peripheral nerve sheath tumors that arise from schwann cells and intraneural fibroblasts. Solitary NF are extremely rare with only a few reported cases in the literature that involve the nasal cavity and paranasal sinuses. Due to its slow growth and the non-specific nature of the symptoms, its clinical presentation and diagnosis is often delayed. Here we present a case of a 65 year old female with left sinonasal neurofibroma which was surgically managed in our department successfully. It was 9.5 cm in greatest dimension and weighed 380 gm which is the largest amongst the available published reports that we could find.
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References
Prakash MD, Viswanatha B, D’Souza GE. A rare case of isolated nasal neurofibroma mimicking sinonasal polyp. Res Otolaryngol. 2014;3(3):49-51.
Hillstrom RP, Zarbo RJ, Jacobs JR. Nerve sheath tumors of the paranasal sinuses: electron microscopy and histopathologic diagnosis. Otolaryngol Head Neck Surg. 1990;102(3):257-63.6.
Perzin K, Panyu H, Wechter S. Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx: A clinicopathological study. XII: Schwann cell tumors (neurilemoma, neurofibroma, malignant schwannoma). Cancer. 1982;50:2193-202.
Adnane C, Adouly T, Elhani L, Mahtar M. Solitary neurofibroma of the maxillary sinus: A rare case report. J Head Neck Physicians Surgeons. 2014;2(2):136-41.
Sharma SB, Hong P. Solitary neurofibroma of the frontal sinus. Case Rep Otolaryngol. 2012;2012.
Azani AB, Bishop JA, Thompson LD. Sinonasal tract neurofibroma: a clinicopathologic series of 12 cases with a review of the literature. Head Neck Pathol. 2015;9:323-33.
Riveros AC, Proietti V, Serrano C, Ruggeri CS. Sinonasal Schwannomas. J Otolaryngol Rhinol. 2021;7:108.
Yap D, Fox H, Addams-Williams J. Unusual case of a Proptosed eye: isolated right Maxillary Neurofibroma. Case Rep Pathol. 2016;2016:4294729.
