Rare case of extra nasopharyngeal angiofibroma arising from tonsil-case report

Authors

  • Udhaya Sankaran Sankarapandian Department of ENT, Burjeel Hospital, Abudhabi, UAE
  • Hiran Kattilaparambil Ravindran Department of Pathology, Burjeel Medical City, Abudhabi, UAE

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20232829

Keywords:

Angiofibroma, Extra nasopharyngeal, Tonsil

Abstract

Angiofibroma is a highly vascular tumour. It occurs in adolescent males mainly in nasopharynx. Due to aggressive local growth, skull base location and risk of profound haemorrhage, management is challenging. Angiofibromas have been sporadically described in extra nasopharyngeal locations. Presentation varies depending upon the location of origin. Here we present a case of 7 year old boy presenting with difficulty in breathing with lump in the throat for 3 years, which has progressively increased in 4 months period with recurrent chocking while sleeping. Initially he was diagnosed with polyp arising from the tonsil. Polyp along with tonsil excised completely. Histopathology confirmed extra nasopharyngeal angiofibroma (ENA). To the best of our knowledge, only 3 cases arising from tonsil had been reported in English literature.

References

De Barros Baptista MAF, De Rezende FP, Voegels RL. Extranasopharyngeal Angiofibroma Originating in the Inferior Turbinate: A Distinct Clinical Entity at an Unusual Site. Int Arch Otorhinolaryngol. 2014;18(04):403-5.

Celik B, Erisen L, Saraydaroglu O, Coskun H. Extranasopharyngeal angiofibroma of nasal septum. A controversial entity. Int J Paediatr Otorhinolaryngol. 2005;69(3):

Arulappan LAS. Extranasopharyngeal angiofibroma in an adolescent male: a case report. Int J Otorhinolaryngol Head Neck Surg. 2019;5:1416-8.

Scholfield DW, Brundler MA, McDermott AL, Mussai F, Kearns P. Adjunctive Treatment in Juvenile Nasopharyngeal Angiofibroma: How Should We Approach Recurrence? J Pediatr Hematol Oncol. 2016;38(3):235-9.

Szymańska A, Szymański M, Morshed K, Czekajska-Chehab E, Szczerbo-Trojanowska M. Extranasopharyngeal angiofibroma: clinical and radiological presentation. Eur Arch Otorhinolaryngol. 2013;270(2):655-60.

Lloyd G, Howard D, Phelps P, Cheesman A. Juvenile angiofibroma: the lesson of 20 years of modern imaging. J Laryngol Otol. 1999;113:127-34.

Ikubor JE, Okolugbo NE, Okhakhu AL. Radiological features of juvenile nasopharyngeal angiofibroma. J West Afr Coll Surg. 2013;3(4):84-91.

Windfuhr JP, Remmert S. Extranasopharyngeal angiofibroma: etiology, incidence and management. Acta Otolaryngol. 2004;124(8):880-9.

Türk B, Ünsal Ö, Akpınar M, Başak ŞT, Coşkun BU. Extra nasopharyngeal Angiofibroma Localized in the Nasal Dorsum: A Rare Location for This Tumor. Sisli Etfal Hastan Tip Bul. 2018;52(3):229-31.

Behera G, Gupta V, Mishra UP, Tandon A. Extra Nasopharyngeal Angiofibroma Arising from Oropharynx: A Clinical Report. Indian J Otolaryngol Head Neck Surg. 2022;74(3):4646-8.

Hallur NH, Zainab H, Shah A, Siddiqua A. Parotid angiofibroma. J Oral Maxillofac Pathol. 2014;18(2):295-8.

Ali E, Fariba S, Mohammad R. Pak J Med Sci. 2008;1(24):2

Tsunoda A, Kohda H, Ishikawa N, Komatsuzaki A. Juvenile angiofibroma limited to the sphenoid sinus. J Otolaryngol. 1998;27:37-9.

Khalid B, Lachkar A, Bouamama T, Miry A, Benfadil D, Ghailan MR. Angiofibroma of the external auditory canal: a rare case with literature review. J Surgical Case Rep. 2002(4):rjac117.

Lee BH. Parapharyngeal Angiofibroma: A case Report. Iran J Radiol. 2015;12(3):e17353.

Steele MH, Nuss DW, Faust BF. Angiofibroma of the larynx: report of a case with clinical and pathologic literature review. Head Neck. 2002;24:805-9.

Windfuhr JP, Remmert S. Extra nasopharyngeal angiofibroma: etiology, incidence and management. Acta Otolaryngol. 2004;124:880-89.

Laine FJ, Nadel L, Braun IF. CT and MR imaging of the central skull base. Part 1: Techniques, embryologic development, and anatomy. Radiographics. 1990;10(4):591-602.

Liu Z, Wang J, Wang H, Wang D, Hu L, Liu Q, Sun X. Hormonal receptors and vascular endothelial growth factor in juvenile nasopharyngeal angiofibroma: immunohistochemical and tissue microarray analysis. Acta Otolaryngol. 2015;135(1):51-7.

Mishra A, Singh V, Verma V, Pandey S, Trivedi R, Singh HP, Kumar S, Dwivedi RC, Mishra SC. Current status and clinical association of beta-catenin with juvenile nasopharyngeal angiofibroma. J Laryngol Otol. 2016;130(10):907-13.

Downloads

Published

2023-09-05

Issue

Section

Case Reports