Schwannoma of oral tongue


  • Sumana C. Viswanatha Department of ENT, Mazumdar Shaw Medical Centre, Narayana Health City, Bangalore, Karnataka, India
  • Nisheena Raghavan Department of Pathology, Mazumdar Shaw Medical Centre, Narayana Health City, Bangalore, Karnataka, India



Schwannoma, Neurilemmoma, Tongue


Schwannomas also known as Neurilemmoma, are benign encapsulated slow growing tumors, which arise from Schwann cells of the peripheral nerve sheath. They usually occur in the head and neck region, but rarely in the oral cavity. We report a case of Schwannoma of the oral tongue in a 49-year-old male patient, who presented with a slow growing, painless lesion involving left side of the dorsum of the oral tongue. Patient underwent Magnetic Resonance Imaging with contrast followed by complete surgical excision. Histopathological and Immunohistochemical examination confirmed the diagnosis.


Cohen M, Wang B. Schwannoma of the tongue: two case reports and review of the literature. Eur Arch Otorhinolaryngol. 2009;266:1823-9.

Zachariades N. Schwannoma of the oral cavity: review of the literature and report of a case. J Oral Med 1984;39:41-3.

Kragh LV, Soule EH, Masson JK. Benign and malignant neurilemmomas of the head and neck. Surg Gynecol Obstet. 1960;111:211-8.

Hatziotis JC, Asprides H. Neurilemoma (schwannoma) of the oral cavity. Oral Surg Oral Med Oral Pathol. 1967;24:510-26.

Moreno-Garcia C, Pons-Garcia MA, Gonzalez-Garcia R, Monje-Gil F. Schwannoma of tongue. J Maxillofac Oral Surg. 2014;13:217-21.

Kavcic J, Bozic M. Schwannoma of the tongue. BMJ Case Rep. 2016;2016:799-81.

Enzinger FM, Weiss SW. Benign tumors of peripheral nerves.In: Enzinger FM, Weiss SW, editors. Soft tissue tumors. 4th ed. St. Louis: Mosby; 1995:821-88.

Hwang K, Kim SG, Ahn SI, Lee SI. Neurilemmoma of the tongue. J Craniofac Surg. 2005;16(5):859-61.

Agha-Hosseini F, Moosavi M-S, Aminishakib P, Yousefian M. A fast-growing schwannoma of the tongue in a 15-year-old Iranian male: Review of literature and case report. Clin Case Rep. 2021;9:e04266.

Lira RB, Gonçalves Filho J, Carvalho GB, Pinto CA, Kowalski LP. Lingual schwannoma: case report and review of the literature. Acta Otorhinolaryngol Ital. 2013;33(2):137-40.

Bansal R, Trivedi P, Patel S. Schwannoma of the tongue. Oral Oncol Extra. 2005;41:15-7.

Lollar KW, Pollak N, Liess BD, Miick R, Zitsch RP. Schwannoma of the hard palate. Am J Otolaryngol. 2010;31:139-40.

Enoz M, Suoglu Y, Ilhan R. Lingual schwannoma. J Cancer Res Ther. 2006;2:76-8.

McMenamin ME, Fletcher CD. Expanding the spectrum of malignant change in schwannomas: epithelioid malignant change, epithelioid malignant peripheral nerve sheath tumor, and epithelioid angiosarcoma: a study of 17 cases. Am J Surg Pathol. 2001;25:13-25.

Yun CB, Kim YM, Choi JS, Kim JW. Pediatric schwannoma of the tongue: A case report and review of literature. World J Clin Cases. 2021;9(24):7212-7.

Fisher C. Diagnostic Pathology: Soft Tissue Tumors. 2nd ed. USA: Amirsys; 2011.

Lindberg MR. Diagnostic Pathology: Soft Tissue Tumors. 2nd ed. USA: Amirsys; 2016.

Ashish G, Sundereshan RS, Philip A. Transoral Laser Excision of Schwannoma in Base of Tongue: A Case Report with Review of Literature. Int J Otorhinolaryngol Clin. 2015;7(2):68-71.

Shashikumar T, Tejaswini JS, Bellad S. Ancient schwannoma: a rare intramural intra-lingual lesion. Indian J Otolaryngol Head Neck Surg. 2019;71:816-9.






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