Intratemporal facial nerve neurofibroma: a case report and review of literature

H. Vijayendra; Amro Yousef; Vinay Kumar Vijayendra; Nilesh Mahajan

doi:10.18203/issn.2454-5929.ijohns20231475

Authors

H. Vijayendra Vijaya ENT Care Centre, Superspeciality Otology Centre, Bangalore, Karnataka, India
Amro Yousef Vijaya ENT Care Centre, Superspeciality Otology Centre, Bangalore, Karnataka, India
Vinay Kumar Vijayendra Vijaya ENT Care Centre, Superspeciality Otology Centre, Bangalore, Karnataka, India
Nilesh Mahajan Vijaya ENT Care Centre, Superspeciality Otology Centre, Bangalore, Karnataka, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20231475

Keywords:

Neurofibromas, Facial nerve, Facial palsy, Bell’s palsy

Abstract

Facial nerve neurofibromas (FNN) are a rare benign tumor of facial nerve can arise from anywhere along the course of the facial nerve from the cerebellopontine angle (CPA) to the extracranial branches within the parotid. They are most commonly located in the parotid gland, and FNN in temporal bone are rarely reported. Intratemporal facial neurofibroma arise from facial nerve in internal auditory canal or in Fallopian canal. It usually manifests as progressive facial palsy, but also can present as sudden or repetitive facial palsy mimicking Bell’s palsy. We reported a case of intratemporal facial neurofibroma arising mainly from mastoid segment in 17-year-old female who presented with progressive facial palsy for 3 years. We briefly reviewed previous cases of intratemporal facial neurofibroma reported in the literature to provide a comprehensive understanding of this rare entity.

Metrics

Metrics Loading ...

References

Liu L, Yang S, Liu L, Yang S, Han D, Huang D, et al. Primary tumours of the facial nerve: diagnostic and surgical treatment experience in Chinese PLA General Hospital. Acta Oto-laryngologica. 2007;127(9):993-9.

Souaid JP, Nguyen VH, Zeitouni AG, Manoukian J. Intraparotid facial nerve solitary plexiform neurofibroma: a first paediatric case report. Int J Pediatr Otorhinolaryngol. 2003;67(10):1113-5.

Liu L, Xiang D, Li Y, Sun J. Clinical characteristics and outcomes of intratemporal facial nerve neurofibromas. Am J Otolaryngol. 2015;36(4):565-7.

Rodriguez FJ, Folpe AL, Giannini C, Perry A. Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems. Acta Neuropathologica. 2012;123:295-319.

Dai C, Li J, Guo L, Song Z. Surgical experience of intratemporal facial nerve neurofibromas. Acta Oto-Laryngologica. 2013;133(8):893-6.

Messersmith L, Krauland K. Neurofibroma. In: StatPearls. StatPearls Publishing, Treasure Island (FL); 2022. PMID: 30969529.

Klingebiel R, Djamchidi C, Harder A, Lehmann R, Jahnke V. Neurofibroma in the mastoid segment of the facial canal. ORL. 2002;64(3):223-5.

Fine SW, McClain SA, Li M. Immunohistochemical staining for calretinin is useful for differentiating schwannomas from neurofibromas. Am J Clin Pathol. 2004;122(4):552-9.

Li Y, Liu H, Cheng Y. Subtotal resection of facial nerve schwannoma is not safe in the long run. Acta Otolaryngol. 2014;134:433-6.

Yamamoto E, Ohmura M, Mizukami C, Oiki H, Muneta Y. (1994). Two cases of intratemporal facial neurofibroma. The facial nerve: an update on clinical and basic neuroscience research. Berlin Heidelberg: Springer; 1994: 274-6.

Kim CS, Chang SO, Oh SH. Management of intratemporal facial nerve schwannoma. Otol Neurotol. 2003;24:312-6.

McMonagle B, Turner J, Fagan P. Intratemporal facial neurofibroma. Otol Neurotol. 2006;27(7):1045-6.