DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20173055

Giant cell tumor of the frontal sinus: case report

Ali Alzarei, Majed Assiri, Rabab N. B., Wael Aljoraebi, Ibrahim Sumaily

Abstract


Giant cell tumor (GCT) is an uncommon aggressive primary bone tumor usually affects long bones. It is rarely involving skull bones, and to less extent the frontal bone. Up to date only 3 adult cases reported of the frontal bone, only one of them was occupying the frontal sinus. Here, we present a 49 year old male presented with slowly growing left supraorbital swelling for 3 years. This swelling was a firm mass with destruction of anterior table of frontal bone. Diagnostic radiological work-up showed a mass in left frontal sinus, mass excised with external approach. Reporting this case with its clinical, radiological and histopathological images should add significant material to the literature for further studies of GCT of paranasal sinuses.

Keywords


Giant cell, Bone tumor, Frontal sinus, Paranasal sinus

Full Text:

PDF

References


Campanacci M, Baldini N, Boriani S, Sudanese A. Giant-cell tumor of bone. J Bone Joint Surg Am. 1987;69(1):106–14.

Cooper AS, Travers B. Surgical Essays. London, England: Cox Longman & Co; 1818: 178-9.

Kos CB, Taconis WK, Fidler MW, ten Velden JJ. Multifocal giant cell tumors in the spine: a case report. Spine. 1997;22(7):821-2.‏

Chan J, Gannon FH, Thompson LD. Malignant giant cell tumor of the sphenoid. Ann Diagn Pathol. 2003;7:100–5.

Matushita JP, Matushita JS, Simões LAM, Neto LFC, Matushita CS, Junior JPK Jr. Giant cell tumor of the frontal sinus: case report. Radiologia Brasileira. 2013,46(4):255-8.‏

Hlavácek V, Jolma VH. Giant cell tumors of bone in the E.N.T. organs. Report of two cases in the frontal sinus. Acta Otolaryngol. 1974;77:374–80.

Ulu MO, Biceroglu H, Ozlen F, Oz B, Gazioglu N. Giant cell tumor of the frontal bone in an 18-month-old girl: a case report. Cent Eur Neurosurg. 2010;71(2):104-7.‏‏

Mirra JM. Giant cell tumor (osteoclastoma). Bone Tumors. Philadelphia: Lea & Febiger; 1989: 119–120.

Mendenhall WM, Zlotecki RA, Scarborough MT, Gibbs CP, Mendenhall NP. Giant cell tumor of bone. Am J Clin Oncol. 2006;29(1):96-9.‏

Lee HJ, Lum C. Giant-cell tumor of the skull base. Neuroradiol. 1999;41(4):305-7.‏

Leonard J, Gökden M, Kyriakos M, Derdeyn CP, Rich KM. Malignant giant-cell tumor of the parietal bone: case report and review of the literature. Neurosurgery. 2001;48(2):424-9.‏

Roux S. Giant cell tumors of bone. Rev Rhum Engl Ed. 1998;65(2):139-47.

Jaffe JL, Lichtenstein L, Portis RB. Giant cell tumor of bone: its pathologic appearance, grading, and supposed variants and treatment. Arch Pathol. 1940;30:993–1031.