Plasma cell mucositis masquerading as squamous cell carcinoma- a surgical dilemma: a rare case report and review of literature

Authors

  • Ashish Gopal Department of otorhinolaryngology and Head and Neck Surgery, Maulana Azad Medical College, New Delhi, India
  • Maya Singh Department of otorhinolaryngology and Head and Neck Surgery, Maulana Azad Medical College, New Delhi, India http://orcid.org/0000-0001-6964-1592
  • Ishwar Singh Department of otorhinolaryngology and Head and Neck Surgery, Maulana Azad Medical College, New Delhi, India
  • Sharmana Mandal Department of Pathology, Maulana Azad Medical College, New Delhi, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20223055

Keywords:

Plasma cell mucositis, Squamous cell carcinoma, Plasmacytosis

Abstract

Plasma cell mucositis is a rare, idiopathic, multifocal, benign proliferative disorder affecting upper aerodigestive tract. It is a very rare condition and less than 50 cases reported in literature. A 62 years old female patient reported with complaints of oral discomfort, superficial erosive ulceration on the tongue, and burning sensation on eating food for last 2 years. Initially, Incisional biopsy of the involved mucosal area confirmed the diagnosis of well differentiated squamous cell carcinoma for which hemi-glossectomy was done. However histopathological examination submitted revealed a hyperplastic epithelium with a dense infiltrate of mature polyclonal plasma cells in the superficial layer of lamina propria, for which plasma cell mucositis was made a diagnosis. Plasma cell mucositis is a diagnosis of exclusion, to be differentiated from other infective, reactive, autoimmune, allergic and neoplastic disorders with plasma cell infiltrates. Management includes topical, intralesional, systemic corticosteroids and debulking procedures. Regular follow-up is essential due to the possibility of its clinical persistence and chances of malignant transformation.

Author Biography

Maya Singh, Department of otorhinolaryngology and Head and Neck Surgery, Maulana Azad Medical College, New Delhi, India

senior resident

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Published

2022-11-24

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Section

Case Reports