The smoker’s larynx: a histopathological study
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20223045Keywords:
Vocal cords, Smokers, Hoarseness, Micro laryngeal surgeryAbstract
Background: Larynx of chronic smokers was clinically evaluated under high powered magnification as well as on histopathology to study the effect of fumes of nicotine on the vocal cords.
Methods: 32 chronic smokers undergoing Lewis suspension micro laryngeal surgery were selected from the laryngology clinics of Dayanand Medical College and Hospital, Ludhiana. Intraoperative findings were recorded and the specimens were sent for histopathological examination. The study was undertaken in a period of one and a half years (June 2009-December 2010).
Results: Maximum patients 31% (10 patients) underwent microlaryngeal surgery were smokers in the middle age group (40-50 years) and minimum 9.3% (3 patients) were above 60 years of age. Vocal polyp/polypoidal change was seen in 7 (21.87%) patients was the predominant finding followed by a chronic hypertrophic change 5 (15.62%) patients. leucoplakia 4 (12.5%) cases, tubercular caseation 3 (9.3%), vocal nodules 4 (12.5%) and vocal cysts 1 (3.125%) were the other findings in our series.
Conclusions: Nicotine fumes affect the epithelium of the vocal cord leading to hypertrophic or hyperplastic transition. Vocal cord polypoidal change, squamous cell carcinoma and chronic hypertrophic laryngitis, in that order were the lesion in our series.
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References
Colt HG, Harrell J, Neuman TR, Robbins T. External fixation of subglottic tracheal stents. Chest. 1994;105(6):1653-7.
Shaw H. Tumours of the larynx. Scott-Brown; Diseases of Ear, Nose and Throat, 4th edition. In: Ballantyne, Groves J. London. 1979;421-508.
New GB, Erich JB. Benign tumors of the larynx: A study of seven hundred and twenty-two cases. Arch Otolaryngol. 1938;28(6):841-910.
Kim Davis R, Kelly SM, Parkin JL, Stevens MH, Johnson LP. Selective management of early glottic cancer. The Laryngoscope. 1990;100(12):1306-9.
Ash JE, Schwartz L. The Laryngeal (vocal cord) node. Trans Amer Acad Ophtal Otolaryngol. 1944; 48:323.
Strong MS, Vaughan CW. Vocal cord nodules and polyps—the role of surgical treatment. The Laryngoscope. 1971;81(6):911-23.
Merati AL, Bielamowicz SA. Textbook of laryngology. Plural Publishing. 2006.
Moore P. A short history of laryngeal investigation. Quarterly J Speech. 1937;23(4):531-64.
Moore P. A short history of laryngeal investigation. J Voice. 1991;5(3):266-81.
Wells WA, Castillo JM. Manuel Garcia, inventor of the laryngoscopic method. The Laryngoscope. 1948;58(10):1133-44.
Jako GJ. Laryngoscope for microscopic observation, surgery, and photography: the development of an instrument. Arch Otolaryngol. 1970;91(2):196-9.
Zeitels SM. Universal modular glottiscope system: the evolution of a century of design and technique for direct laryngoscopy. Ann Otol Rhinol Laryngol. 1999;108(9):2-4.
Jako GJ. Laryngoscope for microscopic observation, surgery, and photography: the development of an instrument. Arch Otolaryngol. 1970;91(2):196-9.
Von Leden H. Microlaryngoscopy: a historical vignette. J Voice. 1988;1(4):341-6.
Mackenzie M. The Use of the Laryngoscope in Diseases of the Throat. Lindsay & Blakiston. 1869.
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