Effect of collagen on large traumatic perforation of tympanic membrane
Keywords:Bovine collagen, Tympanic membrane, Traumatic
Traumatic perforation of the tympanic membrane (TPTM) is often encountered in primary care or in the emergency department (ED). Despite several therapeutic and surgical interventions have been described in the literature, but the conservative approach of follow-up until spontaneous recovery is the most common choice.1 We investigated the utility of bovine collagen extraction patching in the large traumatic TM perforation gives better resultthan spontaneous recovery.
Sagiv D, Migirov L, Glikson E, Mansour J, Yousovich R, Wolf M et al. Traumatic Perforation of the Tympanic Membrane: A Review of 80 Cases. J Emergency Med, 2018;54(2):186-90.
Lazovic G, Colic M, Grubor M, Jovanovic M. The application of collagen sheet in open wound healing. Ann Burns Fire Disasters. 2005;18(3):151-6.
Zhang D, Huang Z, Sun P, Huang H, Zhang Y, Dai J et al. Acceleration of Healing of traumatic tympanic membrane perforation in rats by implanted collagen membrane integrated with collagen-binding basic fibroblast growth factor. Tissue Engineering Part A. 2017;23(1-2):20-9.
Lou ZC, Lou ZH, Zhang QP. Traumatic tympanic membrane perforations: a study of etiology and factors affecting outcome. Am J Otolaryngol. 2012;33(5):549-55.