Mucoepidermoid carcinoma of the palate: a rare case report
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20222685Keywords:
Mucoepidermoid carcinoma, salivary gland, hard palateAbstract
The salivary glands home of several tumoral pathologies, diversified by their locations and their histological types. Described as a rare malignant tumor of the accessory salivary glands, more so in the palatine bone; the diagnosis of Mucoepidermoid carcinoma (CME) remains difficult to evoke due to the uncommonness of the clinical signs and the insidious evolution. The purpose of this case report is to discuss the clinical manifestation, diagnosis, treatment and the follow-up plan of this case. A 39-year-old patient, with no prior pathological history, presents with a painless swelling on the palate evolving for 4 years causing swallowing difficulties without any other signs, several clinical, radiographic and histopathological investigations were carried out for excision of the lesion. Biopsy of the lesion confirmed the diagnosis as mucoepidermoid carcinoma of the palate, following which wide surgical excision with adjacent free margins was performed, the additional surgical treatment consisted of bilateral functional lymph node dissection of groups I, II and III. The follow-up of the patient shows a good improvement in the local condition in the 18 months, after 36 radiotherapy sessions and without signs of recurrence. On the control CT scan with placement of an obturator palatal prosthesis to improve the quality of life awaiting a palatal flap. This case report highlights the need for diagnosis and of an appropriate treatment plan in cases of malignant tumors, as this can lead to morbidity and mortality.
References
Marques KD, Andrade FR, Castro LA, Vêncio EF, Mendonça EF, Ribeiro-Rotta RF, et al. Slow-growing palatal mass: a challenging differential diagnosis. J Oral Maxillofac Surg. 2010;68(8):1884-9.
Rice DH. Malignant salivary gland neoplasms. Otolaryngol Clin North Am. 1999;32(5):875-86.
Perez DE, Pires FR, Lopes MA, Almeida OP, Kowalski LP. Adenoid cystic carcinoma and mucoepidermoid carcinoma of the maxillary sinus: report of a 44-year experience of 25 cases from a single institution. J Oral Maxillofac Surg. 2006;64(11):1592-7.
Vedrine PO. Mucoepidermoid carcinoma of the salivary glands in children: about 18 cases including 11 second cancers. Université Henri Poincaré. 2018.
Baglin AC. Histoseminar on ENT tumor pathology, Pathology Crossroads 2004. Report of the French Society of Pathology. Paris, 2004. Available at: http://www.sfpathol.org/histoseminaires-2004.html. Accessed on 13 July 2022.
Namin AK, Moshref M, Shahoon H, Mashhadi A, Khojasteh A. Intraosseous mucoepidermoid carcinoma of the maxilla in a teenager: a case report and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100(6):e93-6.
Johnson B, Velez I. Central mucoepidermoid carcinoma with an atypical radiographic appearance. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(4):e51-3.
Loos D. Central mucoepidermoid carcinoma of the jaw. Dtsch Monatschr Zahnheik. 1913;31:308.
Lee WH, Yoon JH. Mucoepidermoid carcinoma of the hard palate: a rare cause of hypervascular tumor. Yonsei Med J. 2003;44(4):723-6.
Bridonneau T, Quinque É, Zink S. Mucoepidermoid carcinoma of the palate: presentation of two cases and review of the literature. Oral Medicine Oral Surg. 2017;23(1):37-44.
Auriol M, Chomette G, Delcourt A, Bellefqih S, Guilbert F. Mandibular mucoepidermoid tumor. Rev Stomatol Chir Maxillofac. 1985;86(6):414-7.
Flaitz CM. Mucoepidermoid carcinoma of the palate in a child. Pediatr Dent. 2000;22(4):292-3.
Ord RA, Salama AR. Is it necessary to resect bone for low-grade mucoepidermoid carcinoma of the palate? Br J Oral Maxillofac Surg. 2012;50(8):712-4.
Aro K, Leivo I, Mäkitie AA. Management and outcome of patients with mucoepidermoid carcinoma of major salivary gland origin: a single institution's 30-year experience. Laryngoscope. 2008;118(2):258-62.
Perez DE, Pires FR, Lopes MA, Almeida OP, Kowalski LP. Adenoid cystic carcinoma and mucoepidermoid carcinoma of the maxillary sinus: report of a 44-year experience of 25 cases from a single institution. J Oral Maxillofac Surg. 2006;64(11):1592-7.
Brookstone MS, Huvos AG. Central salivary gland tumors of the maxilla and mandible: a clinicopathologic study of 11 cases with an analysis of the literature. J Oral Maxillofac Surg. 1992;50(3):229-36.
