Published: 2022-07-26

Rhino-orbito-cerebral with cutaneous mucormycosis

Mustafa K. Ezzy, Pushkaraj A. Kulkarni, Shivali K. Patekar, Kshitij D. Shah, Renuka A. Bradoo


"Mucormycosis" term is used for a group of fungal diseases caused by the order mucorales. It typically presents as sino-nasal-orbital involvement and rarely involves skin. Management of such cases is quite challenging. Reported here is a case of a young girl, who presented with right eye swelling and reduced vision and got detected with type 1 diabetes mellitus on admission with rare occurrence of cutaneous lesions while on treatment. Direct nasal endoscopy with biopsy was undertaken. KOH and histopathology report was suggestive of mucormycosis, for which the patient was administered intravenous amphotericin B and surgical debridement was carried out. With the accurate application of a multidisciplinary approach with timely investigations, imaging studies, antifungals and debridement, successful outcome in mucormycosis is well within our reach.


Cutaneous mucormycosis, Rhino-cerebral mucormycosis, Amphotericin, Diabetes

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Singh V, Singh M, Joshi C. Rhinocerebral mucormycosis in a patient with type 1 diabetes presenting as toothache: a case report from Himalayan region of India. BMJ Case Rep. 2013;2013:bcr2013200811.

Castrejón-Pérez AD, Welsh EC, Miranda I. Cutaneous mucormycosis. An Bras Dermatol. 2012;92:304-11.

Shah K, Dave V, Bradoo R. Orbital Exenteration in Rhino-Orbito-Cerebral Mucormycosis: A Prospective Analytical Study with Scoring System. Indian J Otolaryngol Head Neck Surg. 2019;71:259-65.

Oladeji S, Amusa Y, Olabanji J. Rhinocerebral mucormycosis in a diabetic case report. J West Afr Coll Surg. 2013;3:93-102.

Sharma A. Presentation and outcome of rhino-orbital-cerebral mucormycosis in patients with diabetes. Postgraduate Med J. 2004;80:670-4.

Maleitzke T, Stahnke K, Trampuz A. A case report of cutaneous mucormycosis of the hand after minor trauma in a patient with acute myeloid leukaemia. Trauma Case Rep. 2019;23:100221.