Head and neck infection, clinicopathological outline


  • Houssein H. Elmatri Department of Otolaryngology, Faculty of Medicine, University of Benghazi, Benghazi, Libya
  • Nabeia A. Gheryani Department of Pathology, Faculty of Medicine, University of Benghazi, Benghazi, Libya




Neck infection, Dental infections, Peritonsillar abscess


Background: Despite the antimicrobial drugs, a significant percentage of head and neck infection still can be recorded, this study try to identify the causes of recorded cases of head and neck infection in antibiotics era by focusing on the clinical presentation and the predisposing factors.  

Methods: A retrospective study was conducted in the department of otolaryngology in university of Benghazi including 84 patients who were diagnosed as head and neck infection. Clinical data, risk factors and managements were discussed in this study. 

Results: The 84 patients with deep cervical infection were studied. The mean age of our patients was 33 years, most of them were males. Some had other co-diseases. Their main complains was severe throat pain. The most common space involved was peritonsillar space and the most common source of infection was tonsillar infection. Only third of the cases showed positive culture results. The most common organism cultured was Staphylococci. The range of hospital stay was 4-11 days. There was no mortality in our series of patients.

Conclusions: Cervical infection is associated with high rate of morbidity and mortality specially in immune-compromised patients, therefore early detection of the disease followed by quick and appropriate management are life-saving measurements. All patients need early broad-spectrum intravenous antibiotics, and most of them need different surgical intervention. As bad oral hygiene, smoking and low immunity are the major risk factors for neck infection, education of the community, especially in rural area, is required.


McDonnough JA, Ladzekpo DA, Yi I, Bond WR, Ortega G, Kalejaiye AO. Epidemiology and resource utilization of ludwig's angina ED visits in the United States 2006-2014. Laryngoscope. 2019;129(9):2041-4.

Alegbeleye BJ. Deep neck infection and descending mediastinitis as lethal complications of dentoalveolar infection: two rare case reports. J Med Case Rep. 2018;12(1):195.

Wilkie MD, De S, Krishnan M. Defining the role of surgical drainage in paediatric deep neck space infections. Clin Otolaryngol. 2019;44(3):366-71.

Jain A, Singh I, Meher R, Raj A, Rajpurohit P, Prasad P. Deep neck space abscesses in children below 5 years of age and their complications. Int J Pediatr Otorhinolaryngol. 2018;109:40-3.

Boscolo-Rizzo P, Da Mosto MC. Submandibular space infection: a potentially lethal infection. Int J Infect Dis. 2009;13:327-33.

Wang L‑F, Kuo W‑R, Tsai S‑M, Huang K‑J. Characterizations of life threatening deep cervical space infections: a review of one hundred ninety-six cases. Am J Otolaryngol. 2003;24:111‑7.

Caccamese JF, Coletti DP. Deep neck infections: clinical considerations in aggressive disease. Oral Maxillofacial Surg Clin N Am. 2008;20:367-80.

Bakir S, Tanriverdi MH, Gun R, Yorgancilar AE, Yildirim M, Tekbas G, et al. Deep neck space infections: A retrospective review of 173 cases. Am J Otolaryngol. 2012;33(1):56-63.

Daramola OO, Flanagan CE, Maisel RH, Odland RM. Diagnosis and treatment of deep neck space abscesses. Otolaryngol Head Neck Surg. 2009;141:123-30.

Marioni G, Staffieri A, Parisi S, Marchese-Ragona R, Zuccon A, Staffieri C, et al. Rational diagnostic and therapeutic management of deep neck infections: analysis of 233 consecutive cases. Ann Otol Rhinol Laryngol. 2010;119(3):181-7.

Gujrathi AB, Ambulgekar V, Kathait P. Deep neck space infection - a retrospective study of 270 cases at tertiary care center. World J Otorhinolaryngol Head Neck Surg. 2016;2:208-13.

Parhiscar A, Har-El G. Deep neck abscess: a retrospective review of 210 cases. Ann Otol Rhinol Laryngol. 2001;110(11):1051-4.

Al-Noury K, Lotfy A. Deep neck spaces radiology and review of deep neck infections at King Abdul Aziz University Hospital. EJENTAS. 2010;11:110-27.

Panduranga Kamath M, Shetty AB, Hegde MC, Sreedharan S, Bhojwani K, Padmanabhan K, et al. Presentation and management of deep neck space abscess. Indian J Otolaryngol Head Neck Surg. 2003;55(4):270-5.

Bottin R, Marion G, Rinaldi R, Boninsegna M, Salvadori L, Staffier A. Deep neck infection: a present-day complication. A retrospective review of 83 cases (1998-2001). Eur Arch Oto Rhino Laryngol. 2003;260:576-9.

Lin H, Tsai C, Chen Y, Liang JG. Influence of diabetes mellitus on deep neck infections. J Laryngol Otol. 2006;120:650-4.

Kauffmann P, Cordesmeyer R, Tröltzsch M, Sömmer C, Laskawi R. Deep neck infections: a single-center analysis of 63 cases. Med Oral Patol Oral Cir Bucal. 2017; 22:536-41.

Klug TE, Greve T, Hentze M. Complications of peritonsillar abscess. Ann Clin Microbiol Antimicrob. 2020;19:32

Lee YQ, Kanagalingam J. Bacteriology of deep neck abscesses: a retrospective review of 96 consecutive cases. Singapore Med J. 2011;52(5):351-5.

Huang TT, Tseng FY, Liu TC, Hsu CJ, Chen YS. Deep neck infection in diabetic patients: comparison of clinical picture and outcomes with nondiabetic patients. Otolaryngol Head Neck Surg. 2005;132(6):943-7.






Original Research Articles