Mycobacterial profile and antibiotic susceptibility pattern in chronic suppurative otitis media: a cross- sectional study
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20214897Keywords:
Antibiotic susceptibility pattern, Mycobacterial profile, Chronic suppurative otitis media, Resistance, SensitiveAbstract
Background: Chronic suppurative otitis media (CSOM) is a disease of mucoperiosteal lining of the middle ear cleft. The poor compliance of patients to antibiotic treatment, Incomplete treatment, misuse/improper choice of antibiotics have resulted in changes in susceptibility to antibiotics and also development of resistant strains by microbes to commonly used antibiotics. This study aimed to identify the mycobacteriological profile and determine antibiotic susceptibility pattern in CSOM patients.
Methods: This cross sectional study was conducted on 120 clinically diagnosed cases of CSOM attending otolaryngology department. Ear discharges obtained were processed for microbial culture (aerobic, anaerobic and fungi). Antimicrobial susceptibility testing was done by Kirby–Bauer disc diffusion method.
Results: Of total 120 cases, pathogens were isolated from 114 cases. The commonest aerobic organism isolated was Pseudomonas aeruginosa (34.5%) followed by Staphylococcus aureus (29.4%). Staphylococcus aureus showed maximum sensitivity to erythromycin (70%), followed by cotrimoxazole (62.5%) and ampicillin (55%). Maximum resistance was observed for ciprofloxacin (77.5%), followed by amoxiclave (55%). Pseudomonas aeruginosa showed maximum sensitivity to piperacillin (89.36%) followed by gentamicin (70.2%), amikacin (70.2%), moderate sensitivity to ceftazidime (51.06%); however resistance to carbpenicillin (60%). Ciprofloxacin which is the most prescribed topical antibiotic showing an increase in resistance to causative organisms of CSOM.
Conclusions: Hence, it becomes essential to study each case of CSOM bacteriologically to formulate local antibiotic policy for appropriate use of antibiotics. This will certainly help in achieving a safe ear and to control the organisms developing resistance to prevalent antibiotics.
References
Variya A, Tainwala S, Mathur S. Bacteriology of acute otitis media in children. Indian J Med Microbiology. 2002;20:54-5.
Saranya SK, Vazhavandal G, Ismail M. Bacteriological and mycological profile of chronic suppurative otitis media in a tertiary teaching hospital, Trichy, Tamilnadu. Int J Pharm Sci Invent.2015;4(1):13-9.
Indudharan R, Haq JA, Aiyar S. Antibiotics in chronic suppurative otitis media: a bacteriologic study. Ann Otol Rhinol Laryngol. 1999;108:440-5.
Wasihun AG, Zemene Y. Bacterial profile and antimicrobial susceptibility patterns of otitis media in Ayder Teaching and Referral Hospital, Mekelle University, Northern Ethiopia. Springerplus. 2015;4:701.
Kumar R, Agarwal RK, Gupta S. A microbiological study of chronic suppurative otitis media. Int J Recent Sci Res. 2015;6(7):5487-90.
Kusuma BS, K Venkateswarlu K, Krishna B, Ashokreddy, Prasad RN. Study of bacteriology in chronic suppurative otitis media. Int J Med Res Health Sci. 2013;2(3):510-3.
Hassan O, Adeyemi RE. Astudy of bacterial isolates in cases of otitis media in patients attending OAUTHC Ile- Ife. Afr J Clin Exp Microbiol. 2007;8(3):130-6.
Mohammad AH. Chronic suppurative otitis media: microbial and antimicrobial findings. Int J Adv Res. 2016;4:1315-20.
Poorey VK, lyer A. Study of bacterial flora in CSOM and its clinical significance. Indian J Otolaryngol Head Neck Surg. 2002;54(2):91-5.
Jayanthi S. Bacterial and fungal etiology of chronic suppurative otitis media. Int J Res Health Sci. 2013;1(3):199-203.
Vishwanath S, Mukhopadhyay C, Prakash R, Pillai S, Pujary K, Pujary P. chronic suppurative otitis media: Optimisin initial antibiotic therapy in a tertiary care setup. Indian J Otolaryngol Head Neck Surg. 2012;64(3):285-9.
Loy AHC, Tan AL, Lu PKS. Microbiology of chronic suppurative otitis media in Singapore. Singapore Med J. 2002;43(6):296-9.
Deb T, Ray D. A study of bacteriological profile of chronic suppurative otitis media in Agartala. Indian J Otolaryngol Head Neck Surg. 2012;64(4):326-9.
Kumar GS. Investigative profile in patients of chronic suppurative otitis media. Indian J Otol. 1997;3(2):59-62.
Pollock M. Special role pseudomonas aeruginosa in CSOM: workshop on CSOM etiology and management. An Otorhinolaryngol. 1996;17:6.
Kumar R, Srivastava P, Sharma M, Rishi S, Nirwan PS, Hemwani K. Isolation and antimicrobial sensitivity profile of bacterial agents in chronic suppurative otitis media patients at NIMS hospital, Jaipur. Int J Pharm Biol Sci. 2013;3(4):265-9.
Perween N, Kamlakant, Sehgal S, Prakash SK. Aerobic Bacteriology of Chronic Suppurative Otitis Media(CSOM) in A Tertiary Care Hospital in North India. JMSCR. 2014;2(2):395-8.
Sharma K, Agrawal A. Comparison of bacteriology in bilaterally discharging ears in chronic suppurative otitis media. Indian J Otolaryngol Head Neck Surg. 2010;62(2):153-7.
Sharma V, Kaur G. Microbiology and antimicrobial susceptibility pattern of cases of chronic suppurative otitis media in a tertiary care teaching hospital. Int J Bioassays. 2014;3(5):3033-5.
