Published: 2021-11-25

A clinicopathological study and management of tumor and tumor like lesions of larynx

Varunkumar Jayakumar, Jaiswal Shubhalaxmi Atmaram


Background: The aim of the study was to (a) determine the incidence and distribution of cases according to age, sex, etiology etc; (b) to know common etiology for the different diseases; (c) to understand pathophysiology of the disease; (d) to know various presentations of the disease; (e) to determine various diagnostic tools; and (f) to know modalities of treatment available.

Methods: Prospective observational study, method of sampling: non-random, purposive. department of ENT, Government medical college and tertiary care centre. Fifty-one patients with benign and malignant lesion of larynx were analysed. Only cases with persistent hoarseness for more than three weeks were selected. Benign lesions included neoplastic and non-neoplastic lesions. All cases underwent a thorough ENT examination. Once suspected the cases were examined under direct laryngoscope, fibreoptic laryngoscope and if needed microlaryngeal examination was also done.   

Results: The study showed 86.6% benign lesions and 41.1% malignant lesions of larynx with male preponderance. It was observed that vocal polyp was the commonest benign non-neoplastic lesion and papilloma was the commonest neoplastic lesion. Squamous cell carcinoma accounted predominantly in malignant lesions and was commonly found in glottis.

Conclusions: Thus, this study reflects there is an urge to raise awareness and educate people regarding detrimental effects of vocal abuse, alcohol and tobacco consumption, preventive measures, early symptoms and availability of diagnostic tools, so that early diagnosis and appropriate treatment can be executed to reduce the morbidity and mortality.


Laryngectomy, Tracheostomy, Clinicopathological study of larynx lesions

Full Text:



Beasley N. Anatomy of the larynx and tracheobronchial tree. In: Gleesen M, eds. Scott- Brown’s Otolaryngology, Head and Neck Surgery. 7th ed. Great Britain: Hodder Arnold; 2008: 2130-2144.

Sharma DK, Sohal BS, Bal MS, Aggarwal S. Clinico-pathological study of 50 cases of tumours of larynx. Indian J Otolaryngol Head Neck Surg. 2013;65(1):29-35.

Hegde MC, Kamath MP, Bhojwani K, Peter R, Babu PR. Benign lesions of larynx-A clinical study. Indian J Otolaryngol Head Neck Surg. 2005;57(1):35-8.

Singhal P, Bhandari A, Chouhan M, Sharma MP, Sharma S. Benign tumors of the larynx: a clinical study of 50 cases. Indian J Otolaryngol Head Neck Surg. 2009;61(1):26-30.

Kumar JS, Bhutia NN, Bhutia TJ, Malik P, Singh M, Devi HP, et al. Malignant tumours of the larynx: A clinicopathological study of 30 cases. Middle East J Cancer. 2015;6(2):71-8.

Sathyajit S. Profile of carcinoma larynx patients attending a tertiary care hospital in Western Odisha. J Evol Med Dental Sci. 2013;2(7):683-8.

Jaimanti, Panda NK, Sharma S, Gupta AK, Mann SB. Survival patterns in treated cases of carcinoma larynx in north india - a 10 years followup study. Indian J Otolaryngol Head Neck Surg. 2004;56(2):99-104.

Goiato MC, Fernandes AUR. Risk factors of laryngeal cancer in patients attended in the oral oncology centre of Aracatuba. Braz J Oral Sci. 2005;4(13):741-4.

Chopra H, Kapoor M. Study of benign glottic lesions undergoing microlaryngeal surgery. Indian J Otolaryngol Head Neck Surg. 1997;49(3):276-9.

Kamarashev J, Riess CE, Mosimann J, Läuchli S. Lymphogranuloma venereum in Zurich, Switzerland: Chlamydia trachomatis serovar L2 proctitis among men who have sex with men. Swiss Med Wkly. 2010;140(13):209-12.