Giant unicystic ameloblastoma of maxilla-successful endoscopic management

Sanjeev Mohanty, Manu Vergis, Devipriya V., Haripriya G., Lakshmi Shree Nallapaneni, Pravilika Parachur Nallapaneni


This 32-year-old male patient presented with complaints of restricted mouth opening and gross facial asymmetry owing to the massive jaw swelling on the right side. After a thorough examination, a diagnosis of unicystic ameloblastoma of maxilla. Although, the standard of care surgical approach was through Weber-Fergusson incision, a concerted attempt to excise the tumour with the minimally invasive endoscopic route was made successfully. The patient was symptom free now with complete resolution of swelling on a regular follow up post operatively. This case report highlighted the modern day protocol of organ preservation concepts in surgical management of a rare tumour in otolaryngology practice


Ameloblastoma, Maxilla, Denker’s, Endonasal approach, Unicystic, Facial asymmetry, Infra temporal fossa

Full Text:



Gardner DG, Heikinheimo K, Shear M, Philipsen HP, Coleman H. Ameloblastomas. In: Barnes L, Eveson JW, Reichart P, Sidransky D, eds. WHO classification of tumours: pathology and genetics of head and neck tumours. Lyon: IARC Press; 2005: 296-300.

Nakamura N, Higuchi Y, Mitsuyasu T, Sandra F, Ohishi M. Comparison of long-term results between different approaches to ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;93(1):13-20.

Lau SL, Samman N. Recurrence related to treatment modalities of unicystic ameloblastoma: a systematic review. Int J Oral Maxillofac Surg. 2006;35(8):681-90.

Gardner DG, Pecak AM. The treatment of ameloblastoma based on pathologic and anatomic principles. Cancer. 1980;46(11):2514-9.

Schafer DR, Thompson LD, Smith BC, Wenig BM. Primary ameloblastoma of the sinonasal tract: a clinicopathologic study of 24 cases. Cancer. 1998;82(4):667-74.

ElNaggar AK,Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO Classification of head and neck tumours. 4th ed. Lyon: IARC; 2017.

Hertog D, Waal IV. Ameloblastoma of the jaws: a critical reappraisal based on a 40-years single institution experience. Oral Oncol. 2010;46(1):61-4.

Shahidi SH, Bronoosh P, Daneshbod Y. Follicular ameloblastoma presenting as a sinonasal tumor. Iran Red Crescent Med J. 2012;14(2):113-6.

Ueda M, Kaneda T. Combined chemotherapy and radiotherapy for advanced maxillary ameloblastoma. A case report. J Craniomaxillofac Surg. 1991;19(6):272-4.

Björklund A, Elner Å, Snorradottir M. Ameloblastoma of the maxilla: report of three cases. J Laryngol Otol. 1979;93(11):1105-13.

Williams TP. Management of ameloblastoma: a changing perspective. J Oral Maxillofac Surg. 1993;51(10):1064-70.

Lucas RB. Pathology of tumors of the oral tissues. 4th ed. Edinburgh: Churchill Livingstone; 1984: 31-59.

Barnes L, Eveson JW, Reichart P, Sidransky D. World Health Organization classification of tumors, pathology and genetics. Head and neck tumors. 3rd ed. Lyon: IARC Press; 2005.

Data citation