Carcinosarcoma of the nasopharynx: a case report


  • Monica Kotu Department of Otorhinolaryngology, Sefako Makgatho Health Sciences University, Pretoria, South Africa
  • Ian Paul Olwoch School of Medicine University of Limpopo, Polokwane, South Africa
  • Thabo Kgomo Department of Otorhinolaryngology, Sefako Makgatho Health Sciences University, Pretoria, South Africa



Carcinosarcoma, Nasopharynx, Sinonasal malignancy


Carcinosarcoma is a malignant tumor with a dual histological appearance, a squamous epithelial (sarcomatous), and a mesenchymal component. Carcinosarcomas are characterized by a high recurrence rate, metastatic spread, and high morbidity and mortality. Carcinosarcoma can arise from any squamous epithelial lining but rare in the sino-nasal tract. We are presenting a case of a 19-year-old male with a 3-month history of recurrent epistaxis associated with nasal blockage, anosmia, and bilateral complete loss of vision over a few weeks. Carcinosarcoma of the sino-nasal tract is a rare entity and can mimic any sino-nasal malignancy. The optimal treatment of this disease is controversial and lacks a clear guideline, therefore challenging to the treating oncologists. Carcinosarcoma of the head and neck is a rare and aggressive tumor. It poses diagnostic and treatment challenges.


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Case Reports