Covid associated orbital apex syndrome: Madras ENT Research Foundation experience


  • Manjunatha H. Anandappa Madras ENT Research Foundation (MERF), Chennai, Tamil Nadu, India
  • Sunil Mathews Madras ENT Research Foundation (MERF), Chennai, Tamil Nadu, India
  • Kiran Natarajan Madras ENT Research Foundation (MERF), Chennai, Tamil Nadu, India
  • Raghunandhan S. Madras ENT Research Foundation (MERF), Chennai, Tamil Nadu, India
  • Mohan Kameswaran Madras ENT Research Foundation (MERF), Chennai, Tamil Nadu, India



COVID-19, Diplopia, Ophthalmoplegia, Stroke, Orbital apex syndrome, Mucormycosis


The second wave of corona virus pandemic is currently raging through India since last few weeks. Since last year, COVID-19 has brought in a multitude of challenging manifestations in the ENT regions. One such rare and complex entity is OAS (orbital apex syndrome). This case series highlighted our experience in 2020 with managing two such cases of OAS associated with COVID-19 infection. Their clinical and radiological presentation was discussed and their management protocol was explained with references from relevant literature. Although elderly patients with co-morbidities were considered to have highest risk for COVID-19 associated neurologic and ophthalmic complications earlier, now it was found to affect younger healthy individuals as noted in our cases. Knowledge about such virulent complications of COVID-19 is essential for otolaryngologists, to manage this life-threatening entity in a timely manner.


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Case Series