Screening: a unique study of otorhinolaryngeal manifestations in 400 patients of pulmonary tuberculosis being diagnosed and treated under revised national tuberculosis control programme


  • Rupali . Department of ENT, Government Medical College, Amritsar, Punjab, India
  • Karan Sharma Department of ENT, Government Medical College, Amritsar, Punjab, India
  • Nirmal Chand Kajal Department of Chest and TB, Government Medical College, Amritsar, Punjab, India



Pulmonary tuberculosis, Laryngeal tuberculosis, Tubercular otitis media, Nasal tuberculosis, RNTCP, ATT


Background: Tuberculosis (TB) is primarily a disease of lungs but can affect any part of the body. Among extrapulmonary TB, tuberculosis of otorhinolaryngeal region is uncommon but not rare. Despite the best efforts of the RNTCP, tuberculosis is still a major health problem in India. In our study screening of the pulmonary tuberculosis patients was done to know the incidence and pattern of otorhinoloryngeal manifestations and also to know the treatment outcome after follow up of patient till completion of DOTS therapy under RNTCP.

Methods: This study included 400 pulmonary tuberculosis patients, both sputum positive and sputum negative (200 patients in each group) of newly treated (ND) and previously treated (PT) categories. After complete history, physical and local examination, suspected patients were evaluated for otorhinolaryngeal manifestations of tuberculosis. The diagnosis was confirmed after culture swabs, fine needle aspiration cytology (FNAC) and biopsy for histopathological examination (HPE).

Results: Out of total 400 patients majority of patients belong to 21-30 years age group. Out of total 400 patients, 5 (1.25%) patients were having laryngeal tuberculosis, 1 (0.25%) patient of tubercular otitis media and 2 (0.5%) patients were having nasal TB. Results of our study are consistent with previously done studies despite RNTCP treatment. The treatment outcome was good after completion of ATT.

Conclusions: Every patient of pulmonary TB with complaint related to otorhinolaryngeal region should be examined and followed up with high suspicion of ENT related tuberculosis.

Author Biography

Rupali ., Department of ENT, Government Medical College, Amritsar, Punjab, India

Department of ENT, Amritsar, Punjab,India


Krishnatreya M, Das K, Sharma A, Sharma JD. Primary laryngeal tuberculosis mimicking supraglottic carcinoma. Int J Case Rep Imag. 2013;4(7):354-7.

Kulkarni NS, Gopal GS, Ghaisas SG, Gupte NA. Epidemiological considerations and clinical features of ENT tuberculosis. J Laryngol Otol. 2001;115(7):555-8.

Granich R, Chauhan LS. Status report of the revised national tuberculosis control programme: January 2003. J Indian Med Assoc. 2003;101(3):150-1156.

Souse RT, Briglia MFS, Lima LCN, Carvalho RS, Teixeira LM, Marciao AHR, et al. Frequency of otorhinolaryngologies manifestations in patients with pulmonary tuberculosis. Intl Arch Otorhinolaryngol. 2010;14(2):156-62.

Golden MP, Vikram HR. Extrapulmonary tuberculosis: an overview. Am Fam Physician. 2005;72(9):1761-8.

Sahoo U. A study of the epidemiological pattern of pulmonary tuberculosis patients undergoing treatment at tuberculosis units of Lucknow. Asian J Biomed Pharma Sci. 2015;5(44):19-23.

Pandurang K, Shenoy VS, Bhojwani K, Alva A, Prasad V, Gandia S. Tuberculosis in the head and neck in india: down but not yet dead. J Mycobac Dis. 2014;4(2):148.

Banerjee A, Harries AD, Salaniponi FML. Differences in tuberculosis incidence rates in township and in rural populations in Ntcheu District, Malawi. Transact Royal Soc Tropic Med Hyg. 1999;93(4):392-3.

Ddungu H, Johnson JL, Smieja M, MayanjaKizza H. Digital clubbing in tuberculosis-relationship to HIV infection, extent of disease and hypoalbuminemia. BMC Infect Dis. 2006;6:45.

Gupta KB, Garg S. Use of sputum induction for establishing diagnosis in suspected pulmonary tuberculosis. Ind J Tubercul. 2005;52:143-6.

Rooth VM, Sridevi S, Sudhakar G. Association between smoking, alcoholism and pulmonary tuberculosis. Int J Sci Res. 2015;4(6):516-8.

Michael RC, Michael JS. Tuberculosis in otorhinolaryngology: clinical presentation and diagnostic challenges. Int J Otolaryngol. 2011;2011(686894):1-4.

Ricciardiello F, Martufi S, Cardone M, Cavaliere M, D’Errico P, Iengo M. Otorhinolaryngology-related tuberculosis. Acta Otorhinolaryngologica Italica. 2006;26(1):38-42.

Petersen L, Rogers C. Aminoglycoside-induced hearing deficits: a review of cochlear ototoxicity. South Afr Fam Pract. 2015;57(2):77-82.

Kim YM, Kim AY, Park YH, Kim DH, Rha KS. Eight cases of nasal tuberculosis. Otolaryngol Head Neck Surg. 2007;137(3):500-4.

Wafa A, Olfa BG, Hanen G, Ibtissam B, Sarra Z, Ines H, et al. Extra nodal ENT tuberculosis. Egypt J Ear Nose Throat Allied Sci. 2014;15(3):279-82.

Abdalla HA, Ahmed N. Clinical manifestation of laryngeal tuberculosis. Sudan JMS. 2007;2(4):275-6.

Polok A, Namyslowski G, Scierski W, Czecior E, Mrowka-Kata K, Gac B. Tuberculosis within the laryngologic organs. Pol Merkur Lekarski. 2005;19(111):473-4.

Akkara SA, Singhania A, Akkara AG, Shah A, Adalja M, Chauhan N. A study of manifestations of extrapulmonary tuberculosis in the ENT region. Indian J Otolaryngol Head Neck Surg. 2014;66(1):46-50.






Original Research Articles