A rare case of invasive fungal sinusitis by co-infection of two fungi in a post COVID-19 patient: a case report
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20212906Keywords:
COVID-19, Immuno compromised, Invasive fungal sinusitis, Necrosis, KOH, Debridement, Liposomal amphotericin BAbstract
Invasive fungal rhinosinusitis is a disease of the paranasal sinuses and nasal cavity that typically affects immunocompromised patients in acute fulminant form. Early symptoms can often mimic rhino sinusitis while late symptoms can cause significant morbidity and mortality. With early diagnosis and treatment can increase the patient survival. This case report is of 73 years old diabetic post COVID-19 patients. The patient presented to us was having severe headache and facial pain confined to left side cheek area with loosening of teeth. The patient underwent nasal cavity and biopsy from the maxillary sinus (left side) under local anaesthesia, which confirmed the diagnosis of invasive fungal sinusitis suggestive of co-infection by 2 fungi, aspergillus flavus and mucor. Further, the patient underwent surgical debridement and started on liposomal amphotericin B and patient improved significantly.
Metrics
References
Boyd Gillespie M, Bert W, Malley O. An approach to fulminant invasive fungal rhino sinusitis in the immunocompromised host. Arch otolaryngol head and neck surg. 1998;124(5)520-6.
Invasive fungal sinusits: an overview. Otorhinolaryngol clin: an int j. 2009;1(1)45-7.
Feky M, Gaillard F. Acute invasive fungal sinusitis Radopedis.
Duggal P. In chapter 8 Invasive fungal rhino sinusitis. Am J Rhnol Allergy. 2013.
Gupta AK, Bansal S. Invasive fungal sinusits. Clin rhinol–an int J. 2012;5(2)63-71.
Deshazo RD. Syndromes of invasive fungal sinusitis. Med mycol. 2009;47(1):s309-14.
Middle Brooks EH, Frost CJ. Acute invasive fungal rhinosinsitis- a comprehensive update of CT findings and design of an effective diagnostic imaging model. Am j neuroradiol. 2015;36(8)1529-35.
Gillepsie MB, Malley BW. An approach to fulminant invasive fungal rhinosinusitis in the immunocompromised host. Arch otolaryngol head neck surg. 1998;124:520-26.
De Shazo RD, Chaplin K Swain RE. Fungal sinusitis. N Engl J Med. 1997;337:254-9.
Ponka D. Microscopic potassium hydroxide preparation can. Fam physician. 2014;60(1):57.
Lackner M, Caramelho R. Laboratory diagnosis of mucormycosis- current status and future perceptives future. Microbiol. 2014;9(5)683-95.
Epstein VA, Keen RC. Invasive fungal sinusitis and complications of rhinosinusitis, otolaryngol clnics North Am. 2008;41:497-524.
Moen MO, Lyseng, Williamson KA, Scott LJ. Liposomal amphotericin B a review of its use as empirical therapy in febrile neutropenia and in the treatment of fungal infection. Drugs. 2009;69:361-92.
Langner S, Staber PB, Neimeister P. Posaconazole in the management of refractory invasive fungal infections. Thor clin risk management. 2008;4:747-58.
Offner F. Haematopoietic growth factor in cancer patients with invasive fungal infections. Eur J clin microbiol infectious disease. 1997;16:56-63.