DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20212113

Hearing threshold of patients with chronic kidney disease undergoing haemodialysis

Mohammed Bello Fufore, Abdullahi Musa Kirfi, Abubakar Danjuma Salisu, Musa Thomas Samdi, Abdulhameed Bala Abubakar, Paul Adekunle Onakoya

Abstract


Background: Chronic kidney disease (CKD) has been recognised as a serious public health issue due to its many associated complications, including hearing loss (HL). The study aimed to determine the hearing threshold of adult patients with CKD undergoing haemodialysis.

Methods: This was a prospective, hospital-based study of patients with CKD undergoing haemodialysis in a tertiary hospital in Kaduna, carried out between December 2017 and November 2018. Ethical approval and informed consent were obtained. Data was analysed using SPSS version 20. Statistical analysis was with t test and Chi square and level of significance was set at p<0.05.

Results: Thirty patients with CKD undergoing haemodialysis were age and sex matched with 30 controls (CKD patients not on dialysis). Mean age for subjects and controls were 44.6±14.3 and 41.7±12.5, respectively. Mean right ear pure tone average (PTAv) among subjects and the controls were 32.7±9.6 and 25.6±6.2, respectively. Mean left ear PTAv among subjects and controls were 33.3±9.7 and 25.8±6.2, respectively. Hearing loss was present in 73.3% and 41.7% among the subjects and controls respectively (p<0.001). Of the 22 ears of subjects that had ≤10 sessions of dialysis, 13 (59.1%) ears had HL and of the 38 ears that had >10 sessions of dialysis, 30 (78.9%) ears had HL. The difference between hearing threshold and sessions of dialysis was statistically significant (p=0.001).

Conclusions: Hearing thresholds of CKD patients on dialysis was higher than those not on dialysis. Haemodialysis significantly affects the hearing thresholds of CKD patients.

 


Keywords


Chronic kidney disease, Haemodialysis, Hearing loss

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References


Okoye OA, Oviasu E, Ojogwu L. Prevalence of chronic kidney disease and its risk factors amongst adults in a rural population in Edo State, Nigeria. J US Chi Med Sci. 2011;8(81):471-81.

Afolabi M, Abioye-Kuteyi E, Arogundade F, Bello I. Prevalence of chronic kidney disease in a Nigerian family practice population. SA Fam Pract. 2009;51(2):132-7.

Costa K, Ferreira S, Menezes P. Hearing handicap in patients with chronic kidney disease: a study of the different classifications of the degree of hearing loss. Braz J Otorhinolaryngol. 2017;83(5):580-4.

Alport CA. Hereditary familial congenital haemorrhagic nephritis. Br Med J. 1927;1(3454):504-6.

El-Anwar M, Elsayed H, Khater A, Nada E. Audiological findings in children with chronic renal failure on regular hemodialysis. Egypt J Otolaryngol. 2013;29(3):182-8.

Lopez PS, Silva CD, Martin L, Montovani JC. Could the type of treatment for chronic kidney disease affect the auditory system? Brazilian J Otorhinolaryngol. 2014;80(1):54-9.

Klagenberg K, Zeigelboim B, Liberalesso P, Sylvestre L, Marques J, Carvalho H, et al. Vestibular dysfunction in adolescents and young adults after kidney transplant. Int Tinnitus J. 2013;18(2):149-55.

Reddy EK, Prakash SDR, Ramakrishna MG. Proportion of hearing loss in chronic renal failure: our experience. Indian J Otol. 2016;22(1):4-9.

Thodi C, Thodis E, Danielides V, Pasadakis P, Vargemezis V. Hearing in renal failure. Nephrol Dial Transplant. 2006;21(11):3023-30.

Lasisi A, Salako B, Osowole O, Osisanya W, Amusat M. Effect of hemodialysis on the hearing function of patients with chronic renal failure. Afr J Health Sci. 2008;13(3):29-32.

Lasisi OA, Salako BL, Kadiri S, Arije A, Oko-Jaja R, Ipadeola A, et al. Sudden sensorineural hearing loss and hemodialysis. Ear Nose Throat J. 2006;85(12):819-21.

Stavroulaki P, Nikolopoulos TP, Psarommatis I, Apostolopoulos N. Hearing evaluation with distortion-product otoacoustic emissions in young patients undergoing haemodialysis. Clin Otolaryngol Allied Sci. 2001;26(3):235-42.

Gatland D, Tucker B, Chalstrey C, Keene M, Baker L. Hearing loss in chronic renal failure hearing threshold changes following haemodialysis. J R Soc Med. 1991;84(10):587-9.

Alebiosu CO, Ayodele OO, Abbas A, Olutoyin IA. Chronic renal failure at the Olabisi Onabanjo university teaching hospital, Sagamu, Nigeria. Afr Health Sci. 2006;6(3):132-8.

Wong TW, Yu TS, Chen WQ, Chiu YL, Wong CN, Wong AHS. Agreement between hearing thresholds measured in non-soundproof work environment and a soundproof booth. Occup Environ Med. 2003;60(9):667-71.

Adekwu A, Ezeanolue BC, Agaba EI, Adoga AS, Adoga AA. Effect of haemodialysis on hearing functions in adult chronic kidney disease patients in a tertiary hospital in Nigeria. J Med Res Pract. 2014;3(2):46-9.

Sharma R, Gautam P, Narain A, Gaur S, Tiwari R, Lalchandani T. A study on hearing evaluation in patients of chronic renal failure. Indian J Otol. 2011;17(3):109-12.

Risvi S, Holmes R. Hearing loss from haemodialysis. Arch Otolaryngol. 1980;106(12):751-6.

Bendo E, Resuli M, Metaxas S. Hearing evaluation in patients with chronic renal failure. J Acute Disease. 2015;4(1):51-3.

Saeed HK, Al-Abbasi AM, Al-Maliki SK, Al-Asadi JN. Sensorineural hearing loss in patients with chronic renal failure on hemodialysis in Basrah, Iraq Tzu Chi Med J. 2018;30(4):216-20.

Meena R, Aseri Y, Singh B, Verma P. Hearing loss in patients of chronic renal failure: a study of 100 cases. Indian J Otolaryngol Head Neck Surg. 2012;64(4):356-9.

Fufore MB, Kirfi AM, Salisu AD, Samdi MT, Abubakar AB, Lawal J. Hearing loss in chronic kidney disease: an assessment of multiple aetiological parameters. Otolaryngol. 2020;10(3):393.

Sam SK, Subramaniam V, Pai S, Kallikkadan HH. Hearing impairment in patients with chronic renal failure. J Med Sci Clin Res. 2014;2(2):406-16.

Henrich W, Thompson P, Bergstrom L, Lum GM. Effect of dialysis on hearing acuity. Nephron. 1977;18(6):348-51.

Boateng JO, Boafo N, Osafo C, Anim-Sampong S. Hearing impairment among chronic kidney disease patients on haemodialysis at a tertiary hospital in Ghana. Ghana Med J. 2019;53(3):197-203.

Rahman R, Akhtar N, Khanam A, Alam MR. Prevalence and patterns of hearing loss among chronic kidney disease of various stages in Bangladeshi patients. Am J Med Sci Med. 2016;4(3):53-8.

Balasubramanian C, Santhanakrishnakumar B, Anandan H. A study of hearing loss in chronic renal failure. Int J Sci Stud. 2018;5(10):15-8.

Vilayur E, Gopinath B, Harris D, Burlutsky G, McMahon C, Mitchell P. The association between reduced GFR and hearing loss: a cross-sectional population-based study. Am J Kidney Dis. 2010;56(4):661-9.

Fufore MB, Kirfi AM, Salisu AD, Samdi MT, Abubakar AB, Onakoya PA. Stage of chronic kidney disease and cochlear function: a cross-sectional survey. Niger Postgrad Med J. 2020;27(2):122-6.

Sreedharan S, Prasad S, Bhat J, Chandra M, Salil H, Waheeda C. Hearing loss in chronic renal failure-an assessment of multiple aetiological factors. J Otolaryngol. 2015;5(2):1-10.

Nikolopoulos T, Kandiloros D, Segas J, Nomicos P, Ferekidis E, Michelis K, et al. Auditory function in young patients with chronic renal failure. Clin Otolaryngol Allied Sci. 1997;22(3):222-5.

Esfahani ST, Madani A, Ataei N, Tehrani AN, Mohseni P, Ghanbari Z. Sensorineural hearing loss in children with end-stage renal disease. Acta Med Iranica. 2004;42(5):375-8.

Ozturan O, Lam S. The effect of hemodialysis on hearing using pure-tone audiometry and distortion-product otoacoustic emissions. J Otorhinolaryngol Relat Spec. 1998;60(6):306-13.

Stavroulaki P, Nikolopoulos TP, Psarommatis I, Apostolopoulos N. Hearing evaluation with distortion-product otoacoustic emissions in young patients undergoing haemodialysis. Clin Otolaryngol. 2001;26(3):235-42.