Clinicopathological study of solitary thyroid nodule in Kolhan belt of Jharkhand


  • Rajeev Saxena Department of ENT, MGM Medical college, Jamshedpur, Jharkhand, India
  • Shiwani Kanth Department of ENT, RIMS, Ranchi, Jharkhand, India
  • Rohit kumar Jha Department of ENT, MGM Medical college, Jamshedpur, Jharkhand, India
  • Devandra Jee Department of ENT, MGM Medical college, Jamshedpur, Jharkhand, India



Solitary thyroid nodule, Colloid goitre, Fine needle aspiration cytology


Background: Thyroid disorders are commonly encountered in our daily practice and specially in countries like India and Nepal (foothill areas). There are variety of lesions that can arise within thyroid gland. In such scenario it is important to diagnose neoplastic and non-neoplastic conditions accurately with minimum complications so that proper management can be done as early as possible. The aim of the study was to know clinical spectrum of solitary thyroid nodules and diagnostic accuracy of fine needle aspiration cytology as compared to histopathological examination.

Methods: We conducted our study over a period of 21 months from July 2018 to March 2020. 74 patients who gave consent and presented with solitary thyroid swelling were included in the study.  

Results: In our study, cases mostly presented in the age group of 31-40 years with a female preponderance. Colloid goiter was the most common pathology which presented as solitary thyroid nodule. Among neoplastic lesions, follicular adenoma was the most common benign neoplasia with papillary thyroid carcinoma being the most common malignancy. FNAC had sensitivity of 78%, specificity-100%, positive predictive value-100%, negative predictive value-88% and diagnostic accuracy-92%.

Conclusions: Majority of solitary thyroid nodules are found in females of middle age group. In our study we found FNAC as valuable diagnostic tool specially in benign cases.




Patel S, Gattani VJ, Nitnaware AZ. Clinicopathological study of thyroid swelling and its management. Int J Otorhinolaryngol Head Neck Surg. 2020;6:727-31.

Prabha AG. A Clinicopathological study of solitary nodule thyroid with special reference to imprint cytology. Rajiv Gandhi University of health Sci. 2012.

Varghese S, Vilasiniamma L. Solitary thyroid nodule- incidence and histopathology- a 3-year study. J Evolution Med Dent Sci. 2017;6(88):6153-6.

Babu KGS, Shantharam L. A Clinicopathological Study of Solitary Nodule of Thyroid. Int J Scientific Res. 2014;3(4):307-9.

Dhanaram B, Arunachalam J, Muthukumaraswamy B. A clinicopathological study of solitary nodule of thyroid. Int Surg J. 2017;4(7):2288-90.

Zambudio AR, Rodriguez J, Riquelme J, Soria T, Canteras M, Parrilla P. Prospective study of postoperative complications after total thyroidectomy for multinodular goiters by surgeons with experience in endocrine surgery. Ann Surg. 2004;240(1):18-25.

Godara R, Garg P, Singla S. Thyromegaly: lack of consensus in management. The Internet J of Surg. 2007;10(1):8678.

Haque GS, Hossain MJ, Haque S, Rahman MA. A Clinicopathological Study of Solitary Thyroid Nodule. Med Today. 2019;31(2):85-8.

Islam MS, Siddiquee BH, Akhtar N, Salam KS, Aktaruzzaman M. Comparative study of FNAC and histopathology in the diagnosis of thyroid swelling. Bangladesh J Otorhinolaryngol. 2010;16(1):35-43.

Keshri SP, Kumar S, Thakur S. Clinico-Pathological Study of Solitary Thyroid Nodule with Special Reference to Fine Needle Aspiration Cytology. Int J Sci Res. 2017;6(2):789-94.

Bhamre S, Chaudhari S. Clinical Study of Solitary Nodule of Thyroid at Tertiary Health Centre. MVP J Med Sci. 2019;6(1):15-21

Gupta M, Gupta S, Gupta VB. Correlation of fine needle aspiration cytology with histopathology in the diagnosis of solitary thyroid nodule. J Thyroid Res. 2010;379051.

Samir G, Nibedita SS, Kumar PR, Rajlaxmi P, Swarupjit G. A Clinicopathological Study of Solitary Thyroid Nodule. J Pharm Biomed Sci. 2015;5(03):233-7.

Chetan VR, Veeresalingam B, Kumar MK, Durbesula PT, Rao PS. A study on the clinical manifestations and the incidence of benign and malignant tumors in a solitary thyroid nodule. Int J Res Med Sci. 2013;1(4):429-34.

Susmitha MS, Veena S, Babu RK. Fine Needle Aspiration Cytology of Solitary Thyroid Nodule with Histopathology Correlation. Pacific Group J. 2017;4(6):755-60.

Gupta N, Goswami B, Hunjan PS, Shankar LR, Kakar A. Evaluation of the clinicopathological profile of solitary thyroid nodules: Our experience. Thyroid Res Pract. 2016;1-12.






Original Research Articles