Salivary gland tumours: a retrospective study at a tertiary care centre in South India
Keywords:Salivary gland tumours, Histology of salivary gland, South India
Background: Salivary gland tumors are morphologically and histologically diverse group of lesions and their frequency varies in several parts of the world. Better understanding of these tumours will help in assessing the behaviour and outcomes of lesions of this region. The aim of this study was to analyse the charactertistics of different tumours occurring in the salivary gland in a tertiary care centre in South India.
Methods: A retrospective study was conducted of salivary gland tumors diagnosed from the year 2015 to 2020. Patient age and gender, tumor site and frequency, histopathological diagnosis were evaluated and analysed.
Results: A total of 36 salivary gland tumor cases was identified, 30 (87.3%) of which were classified as benign and 6 (12.7%) as malignant. Most tumors occurred in the parotid gland (81.3%). Pleomorphic adenoma was the most common tumor in 23 patients (63.8%), followed by warthins tumour. The tumors occurred more often in women than men.
Conclusion: The results of the present study reinforce prevalence of salivary gland tumours. The parotid gland is the most common location and pleomorphic adenoma are the most frequent lesions. The malignant tumors also can occur in these glands and good clinical suspicion is necessary.
Reinheimer A, Vieira DS, Cordeiro MM, Rivero ER. Retrospective study of 124 cases of salivary gland tumors and literature review. J Clin Exp Dent. 2019 Nov 1;11(11):1025-32.
Shinde AG, Patil A, More S. Salivary Gland Tumors-A Three Year Retrospective Study. Ann Int Med Den Res. 2019;5(3):33-7.
Sood S, McGurk M, Vaz F. Management of Salivary Gland Tumours: United Kingdom National Multidisciplinary Guidelines. J Laryngol Otol. 2016;130(S2):142-9.
Tytor M, Gemryd P, Wingren S, Grenko RT, Lundgren J, Lundquist PG, et al. Heterogeneity of salivary gland tumors studied by flow cytometry. Head Neck. 1993;15(6):514-21.
PDQ Adult Treatment Editorial Board. Salivary Gland Cancer Treatment (Adult) (PDQ®): Health Professional Version. In: PDQ Cancer Information Summaries. Bethesda (MD): National Cancer Institute (US), 2002. Available at: https://www.ncbi. nlm.nih.gov/books/NBK65952/. Accessed on 8 February 2021.
To VS, Chan JY, Tsang RK, Wei WI. Review of salivary gland neoplasms. ISRN Otolaryngol. 2012 Feb 16;2012:872982.
Noel L, Medford S, Islam S, Muddeen A, Greaves W, Juman S. Epidemiology of salivary gland tumours in an Eastern Caribbean nation: A retrospective study. Ann Med Surg. 2018;36:148-51.
Sowa P, Goroszkiewicz K, Szydelko J, Chechlinska J, Pluta K, Domka W, et al. A Review of Selected Factors of Salivary Gland Tumour Formation and Malignant Transformation. Biomed Res Int. 2018;2018:2897827.
Thoeny HC. Imaging of salivary gland tumours. Cancer Imaging. 2007 Apr 30;7(1):52-62.
Nader ME, Bell D, Sturgis EM, Ginsberg LE, Gidley PW. Facial Nerve Paralysis due to a Pleomorphic Adenoma with the Imaging Characteristics of a Facial Nerve Schwannoma. J Neurol Surg Rep. 2014;75(1):84-8.
Lewis AG, Tong T, Maghami E. Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland. Otolaryngol Clin North Am. 2016;49(2):343-80.
Torabinia N, Khalesi S. Clinicopathological study of 229 cases of salivary gland tumors in Isfahan population. Dent Res J (Isfahan). 2014;11(5):559-63.
Ashkavandi Z, Ashraf MJ, Moshaverinia M. Salivary gland tumors: a clinicopathologic study of 366 cases in southern Iran. Asian Pac J Cancer Prev. 2013;14(1):27-30.
Bobati SS, Patil BV, Dombale VD. Histopathological study of salivary gland tumors. J Oral Maxillofac Pathol. 2017;21(1):46-50.
Zarbo RJ. Salivary gland neoplasia: a review for the practicing pathologist. Mod Pathol. 2002;15(3):298-323.
16. Peel RL, Seethala RR. Pathology of salivary gland disease. In: Myers EN, Ferris RL, ed. Salivary Gland Disorders. Berlin, Germany: Springer; 2007: 33-104.
Sathish N, Mahadev Naveen, Kumar V. A clinical study of the incidence of salivary gland tumors in a tertiary care teaching hospital. ISJ. 2019;6:2110.