DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20164788

Epidemiology of nasal polyps in hilly areas and its risk factors

Manpreet Singh Nanda, Shenny Bhatia, Vipan Gupta

Abstract


Background: Nasal polyps are common nasal disorders with unknown etiology and high recurrence and high prevalence of 1-4% which affect the quality of patient life. The aim of the study was to find out the prevalence of nasal polyps in our hilly region and find out its etiological or risk factors for better prevention and cure of the disease.

Methods: 60 patients with nasal polyps were included in this study and were assessed for age and sex distribution, types of polyps, main clinical symptoms and their duration, their major etiological or risk factors through detailed history taking, physical and nasal examination, anterior and posterior rhinoscopy, diagnostic nasal endoscopy and computerized tomography scan.  

Results: Nasal polyps are more common in males and in middle age group. Most of the common types are bilateral and ethmoidal polyps. Most of the patients were symptomatic with nasal obstruction and nasal discharge as main symptoms. There was strong correlation between nasal polyps and recurrent nasal infection, allergy and asthma. In this region we found familial inheritance of this disease and high rate of polyp recurrence after medical or surgical therapy.

Conclusions: Nasal polyps are common in hilly region with high rate of recurrence with nasal infection, allergy and asthma being the important etiological factors.


Keywords


Allergy, Asthma, Epidemiology, Nasal polyps, Non-steroidal anti-inflammatory drugs

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References


Settipane GA. Epidemiology of nasal polyps. Allergy Asthma Proc. 1996;17:231-6.

Bateman ND, Fahy C, Woolford TJ. Nasal polyps: still more questions than answers. J Laryngol Otol. 2003;117:1-9.

Fokkens WJ, Lund VJ, Mullol J, Bachert C, Alobid I, Baroody F, et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology. 2012;50:1–12.

Alobid I, Cardelus S, Benitez P, Guilemany JM, Roca-Ferrer J, Picado C, et al. Persistent asthma has an accumulative impact on the loss of smell in patients with nasal polyposis. Rhinology. 2011;49:519-24.

Johansson L, Akerlund A, Holmberg K, Melén I, Bende M. Prevalence of nasal polyps in adults: The Sko¨vdepopulation-based study. Ann Otol Rhinol Laryngol. 2003;112:625-9.

Chukuezi AB. Nasal polyposis in Nigerian district hospital. West Afr J Med. 1994;13(4):231-3.

Jiang XD, Li GY, Li L, Dong Z, Zhu DD. The characterization of IL-17A expression in patients with chronic rhinosinusitis with nasal polyps. Am J Rhinol Allergy. 2011;25:171–5.

Larsen K, Tos M. The estimated incidence of symptomatic nasal polyps. Acta Otolaryngol. 2002;122:179-82.

Hashemian F, Farahani F. Frequency of nasal polyposis in chronic rhinosinusitis and role of endoscopic examination in correct diagnosis. Sci J Hamadan Uni Med Sci. 2005;12(3):20-3.

Settipane GA, Chafee FH. Nasal polyps in asthma and rhinitis: a review of 6, 037 patients. J Allergy Clin Immunol. 1977;59:17–21.

Tritt S, McMain KC, Kountakis SE. Unilateral nasal polyposis: Clinical presentation and pathology. Am J Otolaryngol. 2008;29(4):230-2.

Larsen PL, Tos M. Origin of nasal polyps. Laryngoscope. 1991;101:305-12.

Shatkin JS, Delsupehe KG, Thisted RA, Corey JP. Mucosal allergy in the absence of systemic allergy in nasal polyposis and rhinitis: a meta-analysis. Otolaryngol Head Neck Surg. 1994;111:553-6.

Delaney JC. Aspirin idiosyncrasy in patients admitted for nasal polypectomy. Clin Otolaryngol Allied Sci.1976;1:27-30.

Blumstein GI, Tuft Ll. Allergy treatment in recurrent nasal polyposis: its importance and value. Am J Med Sci. 1957;234:269-80.

English G. Nasal polyposis. In: GM E, Editors. Otolaryngology. Philadelphia: Harper and Row; 1985: 1-30.

Hedman J, Kaprio J, Poussa T, Nieminen MM. Prevalence of asthma, aspirin intolerance, nasal polyps and chronic obstructive pulmonary disease in a population based study. Inter J Epidemiol. 1999;28:717-22.

Malloney JR, Collins J. Nasal polyps and bronchial asthma. Br J of Diseases of the chest. 1977;71:1-6.

Ragab A, Clement P, Vincken W. Objective assessment of lower airway involvement in chronic rhinosinusitis. Am J Rhinol. 2004;18:15–21.

Widal F, Abrami P, Lermoyez J. Anaphylaxie et idiosyncrasie. 1992 [Anaphylaxis and idiosyncrasy. 1992]. Allergy Proc. 1993;14:373-6.

Samter M, Beers RF Jr. Concerning the nature of intolerance to aspirin. J Allergy. 1967; 40:281-93.

Samter M, Beers RP. Intolerance to aspirin. Clinical studies and consideration of its pathogenesis. Ann Internal Med. 1968;68:975-83.

Cimmino M, Carvaliere M, Mardone M, Plantulli A, Orefice A, Esposito V, et al. Clinical characteristics and genotype analysis of patients with cystic fibrosis and nasal polyposis. Clin Otolaryngol. 2003;28:125-32.

Drake-Lee AB, Lowe D, Swamston A, Grace A. Clinical profile and recurrence of nasal polyps. J. Laryngol Otol. 1984;98:783-93.

Cohen NA, Widelitz JS, Chiu AG, Palmer JN, Kennedy DW. Familial aggregation of sinonasal polyps correlates with severity of disease. Otolaryngol Head Neck Surg. 2006;134:601-4.