Plasma ascorbic acid therapy and eosinophilic counts in allergic rhinitis: a pilot study

Manish Munjal; Atul Singh; Shubham Munjal; Indu Verma; Abhra Ghosh; Sahil Ahluwalia; Ajit Singh Khurana

doi:10.18203/issn.2454-5929.ijohns20205632

Authors

Manish Munjal Department of ENT HNS, Dayanand Medical College, Ludhiyana, Punjab, India
Atul Singh Resident, Dayanand Medical College, Ludhiyana, Punjab, India
Shubham Munjal Department of Biochemistry, Dayanand Medical College, Ludhiyana, Punjab, India
Indu Verma Department of Biochemistry, Dayanand Medical College, Ludhiyana, Punjab, India
Abhra Ghosh Department of Biochemistry, Dayanand Medical College, Ludhiyana, Punjab, India
Sahil Ahluwalia Intern, Dayanand Medical College, Ludhiyana, Punjab, India
Ajit Singh Khurana Department of ENT HNS, Dayanand Medical College, Ludhiyana, Punjab, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20205632

Keywords:

Allergic rhinitis, Ascorbic acid, Eosinophilic count, Vitamin C

Abstract

Background: Role of plasma ascorbic acid in reducing the eosinophilic counts in subjects of allergic rhinitis was studied.

Methods: 60 patients were randomly selected from the Rhinology clinics of Oto- Rhino- laryngology and Head-Neck services of a tertiary health care facility. Shift in the eosinophilic counts in three groups of patients i.e., allergic rhinitis, placebo and control groups was analyzed and compared. The study was undertaken in a period of 1^1/2 years (June 2009 -January 2010) Blood eosinophilic count as %age of DLC was noted.

Results: The mean eosinophilic count was elevated in allergic patients (8.009±2.91) with respect to that in the controls (4.70±1.26). It reverted to normal with treatment with vitamin C. No change was seen in the placebo group. (5.45±3.56).

Conclusions: Vitamin-c reduces the eosinophilic counts in allergic rhinitis.

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Author Biography

Manish Munjal, Department of ENT HNS, Dayanand Medical College, Ludhiyana, Punjab, India

Professor and Head, Deptt of ENTHNS

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