Changing trends in prevalence of goitre in hilly areas

Manpreet Singh Nanda, Ram Krishan Sharma


Background: Thyroid disorders are the most common endocrine disorders affecting the population worldwide. The aim of the study was to identify the emerging changing trends in prevalence of thyroid lesions in hilly areas to control and prevent goitre in these areas.

Methods: 100 patients with thyroid swelling were taken up in this study. The study included detailed history taking including age and sex, patient’s presenting symptoms, dietary habits, psychological status, complete physical examination and investigations like thyroid functions tests, fine needle aspiration cytology and ultrasonography neck. The findings were noted and analysed.  

Results: More incidence of goitre was seen in females and younger and middle age groups. Hypothyroidism is more prevalent but there is increasing prevalence of hyperthyroidism. Non neoplastic lesions are much more common than neoplastic lesions. There is strong correlation between dietary habits and thyroid disorders. Stress factor has a role in thyroid disorders.

Conclusions: Thyroid disorders are common in hilly regions with age, sex, stress and dietary habits playing an important role in their prevalence.


Goitre, Hyperthyroidism, Hypothyroidism, Thyroid disorders, Thyroid function tests

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Delange F, Burgi H, Chen ZP, Dunn JT. World status of monitoring iodine deficiency disorders control programs. Thyroid. 2002;12:915-24.

Peter PAS eds. Epidemiology of Thyroid dysfunction-hypothyroidism and hyper-thyroidism. Thyroid Int. 2009;2:1-16.

Unnikrishnan AG, Menon UV. Thyroid disorders in India: An epidemiological perspective. Indian J Endocrinol Metabol. 2011;15(2):78-81.

Aminorroaya A, Janghorbani M, Amini A, Hovsepian S, Tabatabaei A, Fallah Z. The prevalence of thyroid dysfunction in an iodine-sufficient area in Iran. Arch Iranian Med. 2009;12:262-70.

Park K. Iodine deficiency disorders. In: Park's text book of Preventive and Social Medicine. 19th edition. Jabalpur: Banarsidas Bhanot; 2007: 510-511.

Gelal B, Aryal M, Das BKL, Bhatta B, Lamsal M, Bara N. Assessment of io-dine deficiency status among school age children of Nepal by urinary iodine assay. South Asian J Trop Med Public Health. 2009;40:538-43.

Abu-Eshy SA, Abolfotouh MA, Al-Naggar YM. Endemic goiter in schoolchildren in high and low altitude areas of Asir region, Saudi Arabia. Saudi Med J. 2001;22:146-9.

Yadav S, Gupta SK, Godbole MM, Jain M, Singh U, V Pavithran P, et al. Persistence of severe iodine-deficiency disorders despite universal salt iodization in an iodinedeficient area in northern India. Public Health Nutr. 2010;13:424-9.

Sharma D, Sharma N, Sharma P, Porwal R, Sharma N, Mittal J. Incidence of thyroid malignancy among goitrous thyroid swelling in Rajasthan. World J Pharm Pharmaceutical Sci. 2014;3(2):1727-33.

Baral N, Lamsal M, Koner BC, Koirala S. Thyroid dysfunc-tion in eastern Nepal. South Asian J Trop Med Public Health. 2002;33:638-41.

Sengupta A, Pal R, Kar S, Zaman FA, Basu M, Pal S. Clinicopathological correlates of incidentally revealed thyroid swelling in Bihar, India. J Pharma Bioallied Sci. 2012;4(1):51-5.

Pradeepkumar NS, Singh R, Joseph NM. Emerging trends in thyroid diseases in Tsunami hit coastal areas of Puducherry and Cuddalore. India J Evol Med Dental Sci. 2012;1(5):857-63.

Tunbridge WMG, Evered DC, Hall R, Appleton D, Brewis M, Clark F, et al. The spectrum of thyroid disease in a community: the Whickham survey. Clin Endocrinol. 1977;7:481-3.

Eggertsen R, Petersen K, Lundberg PA, Nystrom E, Lindstedt G. Screening for thyroid disease in a primary care unit with a thyroid stimulating hormone assay with a low detection limit. Brit Med J. 1988;297:1586-92.

Ameh EA, Nmadu PT. Thyrotoxicosis In Zaria, Nigeria: An Update. East Afr med J. 1997;74(7):433-4.

Das BKL, Baral N, Shyangwa PM, Toora BD, Lamsal M. Altered serum levels of thyroxine, triiodothyronine and thyroid stimu-lating hormone in patients with depression. Kathmandu Univ Med J. 2007;5:330-4.

Ahmed Z, Chaudhary R, Umaru N. Study of prevalence of thyroid lesions in coastal region of Karnataka. J Evol Med Dental Sci. 2013;2(36):6995-7002.

Patil RS, Nimbal NV, Pratima S, Patil SR, Sreekantha, Remya. Histopathological study of thyroid lesions. Int J Pharma Bio Sci. 2013;4(4):1003-20.

Qari FA. Pattern of Thyroid Malignancy At University Hospital In Waestern Saudi Arabia. Saudi med J. 2004;25(7):866-70.

Messele G, Tadesse B. Changes in The Pattern Of Thyroid Surgical Diseases In Zewditu Hospital, Addis Ababa. Ethiop Med J. 2003;41(2):179-84.

Mousavi SJ, Mikaili P, Mehdioghli R. Demographic and histopathological study of the thyroidopathies which led to thyroid surgeries in Urmia Imam Hospital, Northwestern Iran. Annals Biol Res. 2011;2(5):38-43.

Burgess JR, Tucker P. Incidence Trends for Papillary Thyroid Carcinoma And Their Correlation With Thyroid Surgery And Thyroid Fine Needle Aspirate Cytology. Thyroid. 2006;16(1):47-53.

Sinha SN, Sengupta SK. Surgical Thyroid Disease in Papua New Guinea. Aust NZ J Surg.1993;63(11):878-82.

Chaturvedi S, Sanjay M, Gupta P. Assesment of iodine induced Disorders. JIMA. 2006;94:127-35.