DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20205079

A large malignant oncocytoma of parotid gland: a case report

Nidhi Mohan Sreedevi, Sunita S. Vernekar, Mohammed M. Abdus Samee, Manjunath Dandinarasaiah

Abstract


Malignant oncocytoma is an extremely rare neoplasm of the salivary gland accounting for 0.5% of epithelial salivary gland malignancies and 0.18% of epithelial salivary gland tumors. We report a case of malignant oncocytoma of left parotid gland in a 61-year old female patient. Patient presented with a 6-year history of painless swelling in the left parotid region. Fine needle aspiration cytology of the swelling was suggestive of pleomorphic adenoma. A computed tomography scan performed did not reveal any features suggestive of malignancy. Patient underwent left superficial parotidectomy. However, histopathological examination of the specimen turned out to be malignant oncocytoma. Malignant oncocytoma of salivary glands have rare incidence and may have similar morphologic features with other neoplasms. Despite the tumor being large and malignant in this case, there was no facial palsy preoperatively. As histopathology is often diagnostic, the possibility of malignancy always must be kept in mind preoperatively even when there is no facial palsy or fine needle aspiration cytology not showing up malignancy.


Keywords


Malignant oncocytoma, Salivary gland, Tumor

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References


Ardekian L, Manor R, Peled M, Laufer D. Malignant oncocytoma of the parotid gland: case report and analysis of the literature. J Oral Maxillofac Surg. 1999;57:325-8.

Capone RB, Ha PK, Westra WH. Oncocytic neoplasms of the parotid gland: a 16-year institutional review. Otolaryngology--head and neck surgery: official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2002;126:657-62.

Caloglu M, Yurut-Caloglu V, Altaner S. Oncocytic carcinoma of the parotid gland. Onkologie. 2006;29:388-90.

Lin CC, Tsai MH, Huang CC, Hua CH, Tseng HC, Huang ST. Parotid tumors: a 10-year experience. American journal of otolaryngology. 2008;29:94-100.

Leahy T, Sader C. Oncocytic carcinoma of the parotid gland with facial nerve invasion. BMJ case reports. 2011;2011.

Zhou CX, Gao Y. Oncocytoma of the salivary glands: a clinicopathologic and immunohistochemical study. Oral Oncol. 2009;45:e232-8.

Trenkić Božinović M, Krasić D, Katić V, Krstić M. A retrospective review of 139 major and minor salivary gland tumors. Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina. 2015;12:73-8.

Seethala RR, Stenman G. Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Tumors of the Salivary Gland. Head and neck pathology. 2017;11:55-67.

Nakagawa M, Sohma S, Watanabe K, Murakata H, Ishii K. [A case of malignant oncocytoma of the parotid gland]. Nihon Jibiinkoka Gakkai Kaiho. 1996;99:1-5.

Ellis G, Auclair P, Douglas R. Surgical Pathology of the Salivary Glands. Philadelphia: W.B. Saunders. 1991.

Gray SR, Cornog JL Jr, Seo IS. Oncocytic neoplasms of salivary glands: a report of fifteen cases including two malignant oncocytomas. Cancer. 1976;38:1306-17.

Kimura M, Furuta T, Hashimoto S, Takano T, Nagao K. Oncocytic carcinoma of the parotid gland. A case report. Acta cytologica. 2003;47:1099-102.

Brandwein MS, Huvos AG. Oncocytic tumors of major salivary glands. A study of 68 cases with follow-up of 44 patients. Am J Surg Pathol. 1991;15:514-528.

Wierzbicka M, Kopeć T, Szyfter W, Kereiakes T, Bem G. The presence of facial nerve weakness on diagnosis of a parotid gland malignant process. Eur Arch Otorhinolaryngol. 2012;269:1177-82.