DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20205062

Salivary gland tumours: a hospital-based study on demographic and incidence pattern, histopathological types and treatment strategy

M. K. Mili, Hirak Jyoti Das, Asha Saikia, N. J. Saikia, J. Phookan, Mridusmita Gohain

Abstract


Background: Salivary gland tumours constitute 3-4% of all head and neck cancers (mostly benign). These tumours are epithelial (95%) or mesenchymal in origin. Pleomorphic adenoma is the most common benign salivary gland tumour and mucoepidermoid carcinoma (45%) is the most common malignant salivary gland tumour followed by adenoid cystic carcinoma (30%). The parotid, submandibular and the minor salivary glands of palate are commonly involved and the sublingual gland is rarely affected.

Methods: Hospital based cross sectional study was done in a tertiary care centre during a period of 1 year, which included 21 patients (10 men and 11 women). Patients were analysed according to age, gender, food habits, histopathological type and site of the tumour and treatment strategy.

Results: All the cases were from upper Assam province sharing a particular demographic pattern between 19-65 years. Peak incidence in males was fourth decade and females was third decade. Male female ratio was 0.9:1. Out of 21 cases, 14 were parotid gland tumours, 6 submandibular gland tumours and 1 minor salivary gland tumour. Most of the tumours were benign (16) and 5 were malignant.

Conclusions: Two patients were of age 19 years which is conflicting the normal national incidence. All cases belonged to lower economic strata with decreased intake of beta carotene enriched food items. The most common site is parotid gland and most common tumour is pleomorphic adenoma which is in accordance to other studies. Benign cases were subjected to superficial parotidectomy and malignant cases to total parotidectomy with neck dissection.


Keywords


Parotid, Submandibular, Sublingual, Salivary gland

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References


Jude UO, Olu-Eddo AN. Salivary gland tumors, a twenty-year retrospective study. Afr J Med Health Sci. 2014;13:24-9.

Ezeanolue BC. Salivary gland neoplasms: a descriptive analysis of the pattern seen in Enugu. West Afr J Med. 1999;18:179-82.

Zheng W, Shu XO, Ji BT, Gao YT. Diet and other risk factors for cancer of the salivary glands: A population-based case-control study. Int J Cancer. 1996;67(2):194-8.

Laishram RS, Kumar KA, Pukhrambam GD, LaishramS, Debnath K. Pattern of salivary gland tumors in Manipur, India: A 10-year study. South Asian J Cancer. 2013;2:250-3.

Faquin WC, Rossi ED, Baloch Z, Barkan GA, Foschini M, Kurtycz DFI et al editors. The Milan System for Reporting Salivary Gland Cytopathology. Cham: Springer. 2018;1-9.

Kucuk U, Akoz G, Cakir E, Pala EEO, Bayol U, Gumussoy M et al. Documentation of the Salivary Gland Tumors: An Institutional data from Turkey. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;119(3):166.

Eveson JW, Cawson RA. Salivary gland tumours: A review of 2410 cases with particular reference to histological type, site, age and sex distribution. J Pathol. 1985;146:51-8.

Lawal AO, Adisa AO, Kolude B, Adeyemi BF, Olajide MA. A review of 413 salivary gland tumours in the head and neck region. J Clin Exp Dent. 2013;5(5):218-22.

de Oliveira FA, Duarte EC, Taveira CT, Maximo AA, de Aquino EC, Alencar Rd et al. Salivary gland tumor: a review of 599 cases in a Brazilian population. Head Neck Pathol. 2009;3(4):271-5.

Srivani N, Srujana S, Shahista S, Kumar OS. Spectrum of salivary gland tumors - A five-year study. IAIM. 2016;3(7):132-6.

Rahrotaban S, Masoomi P, Moradi M, Sharifpour V. Frequency of salivary gland tumors in two referral center of Qazvin university of Medical sciences from 1999-2009. J Res Dent Sci. 2009;2:27-31.

Satko I, Stanko P, Longauerova I. Salivary gland tumors treated in the stomatological clinics in Bratislava. J Craniomaxillofac Surg. 2000;28:56-61.

Vijayalaxmi M, Swaminadh P, Tati ST, Gattu VR, Nakka A, Avinash C et al. Demographic And Clinico-Pathological Study of Salivary Neoplasms. J Dental Med Sci. 2017;16(10):59-63.

Sardar MA, Ganvir SM, Hazarey VK. A demographic study of salivary gland tumors. SRM J Res Dent Sci. 2018;9:67-73.

Shetty A, Geethamani V. Role of fine-needle aspiration cytology in the diagnosis of major salivary gland tumors: A study with histological and clinical correlation. J Oral Maxillofac Pathol. 2016;20:2249.

Agustin VP, RenĂȘ G, VergĂ­lius AFJF, Vieira de CI. Salivary gland tumors in a Brazilian population: a retrospective study of 124 cases. Rev Hosp Clin. 2002;57(6):271-6.