Role of mitomycin-C in endoscopic dacryocystorhinostomy with lacrimal sac stenting

Authors

  • Jogeshwar Singh Department of Oto-rhino-laryngology-Head Neck Surgery, Dayanand Medical College, Ludhiana, India
  • Manish Munjal Department of Oto-rhino-laryngology-Head Neck Surgery, Dayanand Medical College, Ludhiana, India
  • Sanjeev Puri Department of Oto-rhino-laryngology-Head Neck Surgery, Dayanand Medical College, Ludhiana, India
  • Parth Chopra Department of Oto-rhino-laryngology-Head Neck Surgery, Dayanand Medical College, Ludhiana, India
  • Shubham Munjal Department of Oto-rhino-laryngology-Head Neck Surgery, Dayanand Medical College, Ludhiana, India
  • Akshi Garg Department of Oto-rhino-laryngology-Head Neck Surgery, Dayanand Medical College, Ludhiana, India
  • Hemant Chopra Department of Oto-rhino-laryngology-Head Neck Surgery, Dayanand Medical College, Ludhiana, India
  • Dinesh Garg Department of Opthalmology, Dayanand Medical College, Ludhiana, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20204624

Keywords:

ENDODCR. Mitomycin-C, Stenting

Abstract

Background: This study critically evaluates the effectiveness of mitomycin-C in conventional endoscopic dacryocystorhinostomy (ENDODCR) that minimizes the reclosure of a neo-ostium by retaining an enlarged marsupialized lacrimal sac.

Methods: The combined retrospective and prospective study included 24 patients in the study group, who underwent endoscopic dacryocystorhinostomy in the Department of Otorhinolaryngology and Ophthalmology in a period of 1.5 years (June 2006 to January 2008).  

Results: An 83.33% primary success rate was observed, without any serious complications. Obstruction of the neo-ostium with granulation tissue was observed in 20.83% cases. Overall, the success rate of group I was 91.67% as compared to 75% in group II.

Conclusions: Intra operative mitomycin-C application is effective in increasing the success rate of DCR surgery in standard nasolacrimal duct obstruction, and no significant complications resulted from its use.

Author Biography

Manish Munjal, Department of Oto-rhino-laryngology-Head Neck Surgery, Dayanand Medical College, Ludhiana, India

Professor and Head, Deptt of ENTHNS

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Published

2020-10-23

Issue

Vol. 6 No. 11 (2020): November 2020

Section

Original Research Articles