An unusual case of extensive chondrosarcoma of nasal septum


  • Satish Jain Department of ENT, Jain ENT Hospital, Jaipur, Rajasthan, India
  • Harikrishan B. Department of ENT, Jain ENT Hospital, Jaipur, Rajasthan, India



Chondrosarcoma, Malignant tumour, Surgery, Metastasis


Chondrosarcoma is a very rare malignant tumour of nasal cavity. It is seen commonly in middle aged men. The definitive treatment is surgical resection with wide margins. Radiation and chemotherapy are reserved for residual or recurrent disease and as palliative treatment. Here we present a case of Grade II mesenchymal chondrosarcoma involving both nasal cavities extending into ethmoid, frontal and sphenoid sinuses with intracranial extension and also its surgical management.   


Burkey BB, Hoffman HT, Baker SR, Thornton AF, Clatchey KD. Chondrosarcoma of the Head and Neck. Laryngosc. 1990;100:1301-5.

Scartozzi R, Couch M, Sciubba J. Chondroid Chordoma of the Nasal Septum. Arch Otolaryngol Hea Nec Surg. 2003;129(2):244.

Ellis MA, Gerry DR, Byrd JK. Head and neck chondrosarcomas: Analysis of the Surveillance, Epidemiology, and End Results database: Head and neck chondrosarcomas. Head Neck. 2016;38(9):1359-66.

Lacovara J, Patterson K, Reaman G. Primary nasal chondrosarcoma. The pediatric experience. Americ J Pediat Hematol/Oncol. 1992;14(2):158-62.

Jaswal A, Jana AK, Sikder B, Jana U, Nandi TK. Chondrosarcoma of nose and paranasal sinus - a rare presentation. Indian J Otolaryngol Head Neck Surg. 2008;60(3):284-6.

Downey TJ, Clark SK, Moore DW. Chondrosarcoma of the Nasal Septum. Otolaryngol Head Neck Surg. 2001;125(1):98-100.

Nishizawa S, Fukaya T, Inouye K. Chondrosarcoma of the nasal septum: A report of an uncommon lesion. Laryngosc. 1984;94:550-3.

Rassekh CH, Nuss DW, Kapadia SB, Curtin HD, Weissman JL, Janecka IP. Chondrosarcoma of the Nasal Septum: Skull Base Imaging and Clinicopathologic Correlation. Otolaryngol Head Neck Surg. 1996;115(1):29-37.

Bailey C. Chondrosarcoma of the nasal septum. J Laryngol Otol. 1982;96:459-67.

Lichenstein L, Jaffe HL. Chondrosarcoma of Bone. Americ J Pathol. 1943;19(4):553-89.

Lloyd GAS, Phelps PD, Michaels L. The imaging characteristics of naso-sinus chondrosarcoma. Clinic Radiol. 1992;46(3):189-92.

Ceylan K, Kizilkaya Z, Yavanoglu A. Extraskeletal myxoid chondrosarcoma of the nasal cavity. Eur Arch Otorhinolaryngol. 2006;263(11):1044-7.

Prognostic factors in chondrosarcoma of bone. A clinicopathologic analysis with emphasis on histologic grading. 1977;40(2):14.

Yamamoto S, Motoori K, Takano H, Nagata H, Ueda T, Osaka I. Chondrosarcoma of the nasal septum. Skelet Radiol. 2002;31(9):543-6.

Pellitteri PK, Ferlito A, Fagan JJ, Suárez C, Devaney KO, Rinaldo A. Mesenchymal chondrosarcoma of the head and neck. Oral Oncol. 2007;43(10):970-5.

Knott PD, Gannon FH, Thompson LDR. Mesenchymal Chondrosarcoma of the Sinonasal Tract: A Clinicopathological Study of 13 Cases With a Review of the Literature. Laryngosc. 2003;113(5):783-90.

Aretsky PJ, Kantu K, Freund HR, Polisar IA. Chondrosarcoma of the Nasal Septum. Ann Otol Rhinol Laryngol. 1970;79(2):382-8.

Batsakis JG, Dito W. Chondrosarcoma of Maxilla. Arch Otolaryngol. 1962;75(1):55-61.






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