Effect of vitamin D levels in benign paroxysmal positional vertigo

Shweta Sawant, Taranath Nandini, Rajashree Partabad


Background: Benign paroxysmal positional vertigo (BPPV) is a common cause of disabling vertigo with a high rate of recurrence. BPPV is the most common cause of neurotological disorder. It is caused by dislodged otoconia which fall from the utricular macula and float into the semicircular canals there by making them sensitive to gravity. It has been shown that elderly people may suffer from unrecognized, chronic BPPV. Patients with unrecognized BPPV were more likely to have reduced activity of daily living scores, to have sustained a fall in the previous 3 months and to have depression.

Methods: A prospective study of 100 patients with clinical diagnosis of BPPV visiting Navodaya medical college and hospital between June 2019 to May 2020 were included in the study.

Results: Patients taking both vitamin D supplementation and rehabilitation therapy improved better than patients taking rehabilitation therapy alone.

Conclusions: Both rehabilitation therapy and supplementation of vitamin D is helpful in patients with vitamin D deficient BPPV patients.


BPPV, Vitamin D, Otolith disease, Rehabilitation therapy

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White, JA, Coale, KD, Catalano, PJ. Diagnosis and management of lateral semicircular canal benign paroxysmal positional vertigo. Otolaryngol Head Neck Surg. 2005;133:278-84.

Cakir, BO, Ercan, I, Cakir, ZA. What is the true incidence of horizontal semicircular canal benign paroxysmal positional vertigo? Otolaryngol Head Neck Surg. 2006;134:451-4.

Parnes, LS, Agarwal, SK, Atlas, J. Diagnosis and management of benign paroxysmal positional vertigo(BPPV).CMAJ. Ann Med Health Sci Res.2015;5(1):50-3

Vibert D, Kompis M, Hausler R. Benign Paroxysmal Positional Vertigo in older women may be related to osteoporosis and osteopenia. Ann Otol Rhinol Laryngol. 2003;112:885-9.

Mikulec AA, Kowalczyk KA, Pfitzinger ME, Harris DA, Jackson LE. Negative association between treated osteoporosis and benign paroxysmal positional vertigo in women. J Laryngol Otol. 2010;124:374-6.

Buki B, Simon L, Garab S, Lundberg YW, Jünger H, Straumann D. Sitting-up vertigo and trunk retropulsion in patients with benign positional vertigo but without positional nystagmus.J Neurol Neurosurg Psychiatry.2011;82:98-104.

Mikulec AA, Kowalczyk KA, Pfitzinger ME, Harris DA, Jackson LE. Negative association between treated osteoporosis and benign paroxysmal positional vertigo in women. J Laryngol Otol. 2010;124:374–6.

Buki B, Ecker M, Lundberg YW. Vitamin D deficiency and benign paroxysmal positional vertigo. Med Hypothesis. 2013;80(2):201-4.

Curthoys IS, Manzari L. Otolithic disease: clinical features and the role of vestibular evoked myogenic potentials. Semin Neurol. 2013;33:231–7.

Yetiser S, Ince D. Demographic Analysis of Benign Paroxysmal Positional Vertigo as a common Public Health Problem. Annals of Medical and Health Sciences Research. 2015;5(1):50-3.

Perez VP, Franco GV. Treatment of benign paroxysmal positional vertigo. A clinical review. J Otol. 2017;12(4):165-73.

Sheikhzadeh M, Lotfi Y, Mousavi A, Heidari B, Monadi M, Bakhshi E. Influence of supplemental vitamin D on intensity of BPPV; A longitudinal clinical study. Caspian J Intern Med. 2016;7(2):93-8.

Ding J, Liu L, Kong WK, Chen XB, Liu X. et al. Serum levels of 25-hydroxy vitamin D correlate with idiopathic benign paroxysmal positional vertigo. Biosci Rep. 2019;39(4):BSR20190142.

Talaat HS, Abuhadied G, Talaat AS, Abdelaal MS. Low bone mineral density and vitamin D deficiency in patients with benign positional paroxysmal vertigo. Eur Arch Otorhinolaryngol. 2015;272:2249-53.

von Brevern M, Radtke A, Lezius F. et al. Epidemiology of BPPV: a population based study. J Neurol Neurosurg Psychiatry 2007;78:710-5.

Parham K, Leonard G, Feinn RS, et al. Prospective clinical investigation of the relationship between idiopathic benign paroxysmal positional vertigo and bone turnover: a pilot study. Laryngoscope. 2013;123:2834-9.