Diagnostic dilemmas of head and neck tuberculosis: our experience and review of literature
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20201690Keywords:
Extrapulmonary tuberculosis, Head and neck, Larynx, Lymph nodes, Ear, MastoiditisAbstract
Background: The aim of the study was to highlight the varied and changing presentations of head and neck tuberculosis, discuss the difficulties in diagnosis and treatment.
Methods: This was a 5 years retrospective analysis of patients with extrapulmonary tuberculosis (EPTB) of the head and neck region.
Results: 54 patients with EPTB were studied. Most had cervical lymphadenopathy (35), 9 had laryngeal, 7 tuberculous otitis media, and one patient each of PNS, oropharyngeal and retropharyngeal involvement. 8 patients had pulmonary TB, 2 had Potts spine, and 5 gave history of previous TB. FNAC was effective in nodal disease, PPD test positive in 11% and HPE was used to make the diagnosis in other types.
Conclusions: TB is re-emerging as a significant cause of morbidity. Diagnosing EPTB requires high index of suspicion. Cervical lymphadenopathy is the commonest presentation, followed by larynx, and then ear. FNAC is a reliable and convenient way to diagnose lymphadenopathy. Hitopathological examination needed for confirmation, and for other sites. Further investigations are needed to exclude pulmonary or systemic TB. All patients should be categorised into proper category of anti-tuberculous treatment (ATT) and treated according to ATT regimen.
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References
Epidemiology of tuberculosis module. Atlanta: CDC National Centre for HIV, STD and TB prevention, division of TB prevention; 2004.
Aaron L, Saadoun D, Calatroni I, Launay O, Memain N, Vincent V, et al. Tuberculosis in HIV-Infected Patients: A Comprehensive Review. Clin Microbiology Inf. 2004;10:388-98.
Serhani AM. Mycobacterial infection of head and neck: presentation and diagnosis. Laryngoscope. 2001;111:2012-16.
Dye C, Garnett GP, Sleeman K, Williams BG. Prospects of worldwide tuberculosis control under the WHO DOTS strategy, Directly Observed Short Course Therapy. Lancet. 1998;352:1886-91.
Ricciardiello F, Martufi S, Cardone M, Cavaliere M, Errico DP, Lengo M. Otolaryngology related tuberculosis. Acta Otorhinolaryngol Ital. 2006;26:38-42.
Fain O, Lortholary O, Lascaux V, Amoura I, Babinet P, Beaudreuil J, et al. Lymph node tuberculosis in suburbs of Paris. Int J Tubec Lung Dis. 1999;3:162-5.
Danbapat MC, Mishra BM, Dash SP, Kar PK. Peripheral lymph node tuberculosis; a review of 80 cases. British J Surg. 1990;77:911-2.
Menon K, Bem C, Gouldesbrough D, Strachan DR. A clinical review of 128 case of Head and Neck Tuberculosis presenting over a 10 years period in Bradford, UK. J Laryngol Otol. 2007;121:362-8.
Bhat N, Vinayak S. Tuberculosis in Ear Nose and Throat practice, its presentation and diagnosis. Am J Otolaryngol Head Neck Med Surg. 2006;27:39-45.
Hunter AM, Miller JW, Wightman AJA, Horne NW. The changing pattern of laryngeal tuberculosis. J Laryngology Otology. 1981;95:393-98.
Bailey MC, Windle TC. Tuberculous laryngitis a series of 37 patients. Laryngoscope. 1981;91:93-9.
Chmeilik LP, Ziolkowski J, Koziolek R, Kulus M, Chmielik M. Ear tuberculosis: clinical and surgical treatment. Int J Pediatric Otolaryngol. 2008;72:271-74.
Lisa MC, Ahmed K, Spinner W, Victor EJ, Susan VD, Eric S. Tuberculous otitis media report of two case on Long island, New York and review of all cases reported in United States from 1990 to 2003. Ear Nose Throat J. 2005;84(8):488-97.
Saunders NC, Albert DM. Tuberculous mastoiditis- when is surgery indicated. Int J Pediatr Otorhinolaryngol. 2002;65:59-63.
Nayar CR, Kaabi JA, Ghorpade K. Primary nasal TB a case report. Ear Nose Throat J. 2004;83:188-91.
Hajioff D, Snow MH, Thaker H, Wilson JA. Primary TB of posterior oropharyngeal wall. J Laryngology Otology. 1999;113:1029-30.
Dilkes M, Gilligan MJ, Chapman J. A rare presentation of TB of the cervical spine. J Laryngol Otol. 1991;105:786-87.